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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Type II iodothyronine deiodinase

SKU : BHE13806099

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0578r
Antigen	DIO2
Alternative Names	5DII ; DIOII ; Type 2 DI ; Type-II 5'-deiodinase ; Itdi2 ; Txdi2
Categories	Elisa
Function	Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
Specificity	Natural and recombinant Rat Type II iodothyronine deiodinase
Subcellular Location	Membrane Single-pass membrane protein
Detection Range	0.156-10ng/mL
Entryname	IOD2_RAT
Method Type	Competitive
Platform	PF00837
Protein Name	Type II iodothyronine deiodinase
Sensitivity	0.05ng/mL
Sequence	50: MGLLSVDLLI ; TLQILPVFFS ; NCLFLALYDS ; VILLKHVALL ; LSRSKSTRGE ; 100: WRRMLTSEGL ; RCVWNSFLLD ; AYKQVKLGED ; APNSSVVHVS ; NPEAGNNCAS ; 150: EKTADGAECH ; LLDFASAERP ; LVVNFGSATU ; PPFTRQLPAF ; RQLVEEFSSV ; 200: ADFLLVYIDE ; AHPSDGWAVP ; GDSSMSFEVK ; KHRNQEDRCA ; AAHQLLERFS ; 250: LPPQCQVVAD ; RMDNNANVAY ; GVAFERVCIV ; QRRKIAYLGG ; KGPFSYNLQE ; 266: VRSWLEKNFS ; KRUILD
Sequence Length	266
String	P70551
Sub Unit	Interacts with USP20 and USP33. Interacts with MARCH6.

Uniprot	P70551
Gene Name	Dio2
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:65162
Unigene	Rn.88380

Reference	1. "Cloning of the mammalian type II iodothyronine deiodinase. A selenoprotein differentially expressed and regulated in human and rat brain and other tissues." Croteau W., Davey J.C., Galton V.A., St Germain D.L. J. Clin. Invest.98:405-417(1996) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;INDUCTION strain: Sprague-Dawley. tissue: Brown adipose tissue. 2. "Induction of type 2 deiodinase activity by cyclic guanosine 3',5'-monophosphate in cultured rat glial cells." Gondou A., Toyoda N., Nishikawa M., Tabata S., Yonemoto T., Ogawa Y., Tokoro T., Sakaguchi N., Wang F., Inada M. Thyroid8:615-622(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 3. "Expression and nocturnal increase of type II iodothyronine deiodinase mRNA in rat pineal gland." Murakami M., Hosoi Y., Negishi T., Kamiya Y., Ogiwara T., Mizuma H., Yamada M., Iriuchijima T., Mori M. Neurosci. Lett.227:65-67(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION 4. "Night/day changes in pineal expression of >600 genes: central role of adrenergic/cAMP signaling." Bailey M.J., Coon S.L., Carter D.A., Humphries A., Kim J.S., Shi Q., Gaildrat P., Morin F., Ganguly S., Hogenesch J.B., Weller J.L., Rath M.F., Moller M., Baler R., Sugden D., Rangel Z.G., Munson P.J., Klein D.C. J. Biol. Chem.284:7606-7622(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806099	E0578r	96T	$796		Add to Cart

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