ELISA Kit for Rat Tropomyosin alpha-4 chain

Mfr.No.	E10254r
Alternative Names	Tropomyosin-4 ; TM-4
Categories	Elisa
Function	Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium.
Specificity	Natural and recombinant Rat Tropomyosin alpha-4 chain
Subcellular Location	Cytoplasm cytoskeleton
Detection Range	0.312-20ng/mL
Entryname	TPM4_RAT
Method Type	Sandwich
Platform	PF00261
Protein Name	Tropomyosin alpha-4 chain
Sensitivity	0.17ng/mL
Sequence	50: MAGLNSLEAV ; KRKIQALQQQ ; ADDAEDRAQG ; LQRELDGERE ; RREKAEGDAA ; 100: ALNRRIQLVE ; EELDRAQERL ; ATALQKLEEA ; EKAADESERG ; MKVIENRAMK ; 150: DEEKMEIQEM ; QLKEAKHIAE ; EADRKYEEVA ; RKLVILEGEL ; ERAEERAEVS ; 200: ELKSSDLEEE ; LKNVTNNLKS ; LEAASEKYSE ; KEDKYEEEIK ; LLSDKLKEAE ; 248: TRAEFAERTV ; SKLEKTIDDL ; EEKLAQAKEE ; NVGLHQTLDQ ; TLNELNCI
Sequence Length	248
String	P09495
Sub Unit	Heterodimer of an alpha and a beta chain.

Reference	1. "Isolation and characterization of cDNA clones encoding a low molecular weight nonmuscle tropomyosin isoform." Yamawaki-Kataoka Y., Helfman D.M. J. Biol. Chem.262:10791-10800(1987) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Structure and complete nucleotide sequence of the gene encoding rat fibroblast tropomyosin 4." Lees-Miller J.P., Yan A., Helfman D.M. J. Mol. Biol.213:399-405(1990) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] tissue: Brain. tissue: Liver. 3. Lubec G., Chen W.-Q. Submitted (2007-02) to the UniProtKB [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY

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BHE13811298	E10254r	96T	$796		Add to Cart