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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Transcription factor 4

SKU : BHE13806507

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1408r
Alternative Names	Immunoglobulin transcription factor 2 ; ITF-2 ; R8f DNA-binding protein ; SL3-3 enhancer factor 2 ; SEF-2 ; Itf2 ; Sef2
Categories	Elisa
Function	Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription (By similarity). Interacts with the CCAAT displacement protein (CDP2) to bind the tyrosine hydroxylase enhancer.
Specificity	Natural and recombinant Rat Transcription factor 4
Subcellular Location	Nucleus
Detection Range	78-5000pg/mL
Entryname	ITF2_RAT
Method Type	Sandwich
Platform	PF00010
Protein Name	Transcription factor 4
Sensitivity	39.6pg/mL
Sequence	50: MTSRDLGSHD ; NLSPPFANSR ; IQSKTERGSY ; SSYGRENVQG ; CHQSLLGGDM ; 100: DMGNPGTLSP ; TKPGSQYYPY ; SSNNARRRPL ; HSSTMEVQTK ; KVRKVPPGLP ; 150: SSVYAPSAST ; ADYNRDSPGY ; SSSKPAASTF ; SSSFFMQDGH ; HSSDPWSSSS ; 200: GMNQPGYGGM ; LGNSHIPQSS ; SYCSLHPHER ; LSYPSHSSAD ; INSSLPPMST ; 250: FHRSGTNHYS ; TSSCTPPANG ; TDSIMANRGT ; GAAGSSQTGD ; ALGKALASIY ; 300: SPDHTNNSFS ; SNPSTPVGSP ; PSLSAGTAVW ; SRNGGQASSS ; PNYEGPLHSL ; 350: QSRIEDRLER ; LDDAIHVLRN ; HAVGPSTAVP ; GGHGDMHGII ; GPSHNGAMGS ; 400: LGSGYGTGLL ; SANRHSLMVG ; AHREDGVALR ; GSHSLLPNQV ; PVPQLPVQSA ; 450: TSPDLNPPQD ; PYRGMPPGLQ ; GQSVSSGSSE ; IKSDDEGDEN ; LQDTKSSEDK ; 500: KLDDDKKDIK ; SITRSRSSNN ; DDEDLTPEQK ; AEREKERRMA ; NNARERLRVR ; 550: DINEAFKELG ; RMVQLHLKSD ; KPQTKLLILH ; QAVAVILSLE ; QQVRERNLNP ; 589: KAACLKRREE ; EKVSSEPPPL ; SLAGPHPGMG ; DTANHMGQM
Sequence Length	589
String	Q62655
Sub Unit	Efficient DNA binding requires dimerization with another bHLH protein. Forms homo- or heterooligomers with myogenin. Interacts with HIVEP2. Interacts with NEUROD2.

Uniprot	Q62655
Gene Name	Tcf4
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:84382
Unigene	Rn.23354

Reference	1. "Identification and analysis of a novel helix-loop-helix transcription factor-encoding gene from Rat forebrain." Diaz M.I., Lopez J., Padilla S., Madrazo J.A., Capo D., Cabrero N., Felix C., Ossorio J., Olmeda Y., Lugo D.I. Submitted (1999-05) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2) tissue: Forebrain. 2. "Isolation of two E-box binding factors that interact with the rat tyrosine hydroxylase enhancer." Yoon S.O., Chikaraishi D.M. J. Biol. Chem.269:18453-18462(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 162-589 (ISOFORMS 1 AND 2) strain: New England Deaconess Hospital. tissue: Adrenal medulla.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13806507	E1408r	96T	$796		Add to Cart

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