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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Toll-like receptor 4

SKU : BHE13810816

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0753r
Alternative Names	CD284
Categories	Elisa
Function	Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Specificity	Natural and recombinant Rat Toll-like receptor 4
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	0.312-20ng/mL
Entryname	TLR4_RAT
Method Type	Sandwich
Platform	PF00560
Protein Name	Toll-like receptor 4
Sensitivity	0.159ng/mL
Sequence	50: MMPLLHLAGT ; LIMALFLSCL ; RPGSLNPCIE ; VLPNITYQCM ; DQNLSKIPHD ; 100: IPYSTKNLDL ; SFNPLKILRS ; YSFTNFSQLQ ; WLDLSRCEIE ; TIEDKAWHGL ; 150: NQLSTLVLTG ; NPIKSFSPGS ; FSGLTNLENL ; VAVETKMTSL ; EGFHIGQLIS ; 200: LKKLNVAHNL ; IHSFKLPEYF ; SNLTNLEHVD ; LSYNYIQTIS ; VKDLQFLREN ; 250: PQVNLSLDLS ; LNPIDSIQAQ ; AFQGIRLHEL ; TLRSNFNSSN ; VLKMCLQNMT ; 300: GLHVHRLILG ; EFKNERNLES ; FDRSVMEGLC ; NVSIDEFRLT ; YINHFSDDIY ; 350: NLNCLANISA ; MSFTGVHIKH ; IADVPRHFKW ; QSLSIIRCHL ; KPFPKLSLPF ; 400: LKSWTLTTNR ; EDISFGQLAL ; PSLRYLDLSR ; NAMSFRGCCS ; YSDFGTNNLK ; 450: YLDLSFNGVI ; LMSANFMGLE ; ELEYLDFQHS ; TLKKVTEFSV ; FLSLEKLLYL ; 500: DISYTNTKID ; FDGIFLGLIS ; LNTLKMAGNS ; FKDNTLSNVF ; TNTTNLTFLD ; 550: LSKCQLEQIS ; RGVFDTLYRL ; QLLNMSHNNL ; LFLDPSHYKQ ; LYSLRTLDCS ; 600: FNRIETSKGI ; LQHFPKSLAV ; FNLTNNSVAC ; ICEYQNFLQW ; VKDQKMFLVN ; 650: VEQMKCASPI ; DMKASLVLDF ; TNSTCYIYKT ; IISVSVVSVL ; VVATVAFLIY ; 700: HFYFHLILIA ; GCKKYSRGES ; IYDAFVIYSS ; QNEDWVRNEL ; VKNLEEGVPR ; 750: FQLCLHYRDF ; IPGVAIAANI ; IQEGFHKSRK ; VIVVVSRHFI ; QSRWCIFEYE ; 800: IAQTWQFLSS ; RSGIIFIVLE ; KVEKSLLRQQ ; VELYRLLSRN ; TYLEWEDNAL ; 835: GRHIFWRRLK ; KALLDGKALN ; PDETSEEEQE ; ATTLT
Sequence Length	835
String	Q9QX05
Sub Unit	Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, LY96 and TLR4. Binding to bacterial LPS leads to homodimerization. Interacts with LY96 via the extracellular domain. Interacts with MYD88 and TIRAP via their respective TIR domains. Interacts with NOX4 (By similarity). Interacts with CNPY3.

Uniprot	Q9QX05
Gene Name	Tlr4
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:29260
Unigene	Rn.14534

Reference	1. "Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium." Frantz S., Kobzik L., Kim Y.-D., Fukazawa R., Medzhitov R., Lee R.T., Kelly R.A. J. Clin. Invest.104:271-280(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Sprague-Dawley. tissue: Heart.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810816	E0753r	96T	$796		Add to Cart

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