ELISA Kit for Rat Thyroxine 5-deiodinase

Mfr.No.	E12263r
Alternative Names	5DIII ; DIOIII ; Type 3 DI ; Type III iodothyronine deiodinase ; Itdi3 ; Txdi3
Categories	Elisa
Function	Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
Specificity	Natural and recombinant Rat Thyroxine 5-deiodinase
Subcellular Location	Cell membrane Single-pass type II membrane protein Endosome membrane Single-pass type II membrane protein
Detection Range	0.156-10ng/mL
Entryname	IOD3_RAT
Method Type	Sandwich
Platform	PF00837
Protein Name	Thyroxine 5-deiodinase
Sensitivity	0.081ng/mL
Sequence	50: MLRSLLLHSL ; RLCAQTASCL ; VLFPRFLGTA ; FMLWLLDFLC ; IRKHFLRRRH ; 100: PDHPEPEVEL ; NSEGEEMPPD ; DPPICVSDDN ; RLCTLASLKA ; VWHGQKLDFF ; 150: KQAHEGGPAP ; NSEVVRPDGF ; QSQRILDYAQ ; GTRPLVLNFG ; SCTUPPFMAR ; 200: MSAFQRLVTK ; YQRDVDFLII ; YIEEAHPSDG ; WVTTDSPYVI ; PQHRSLEDRV ; 250: SAARVLQQGA ; PGCALVLDTM ; ANSSSSAYGA ; YFERLYVIQS ; GTIMYQGGRG ; 278: PDGYQVSELR ; TWLERYDEQL ; HGTRPRRL
Sequence Length	278
Sub Unit	Homodimer. May undergo minor heretodimerization with DIO1 and DIO2.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805973	E12263r	96T	$796		Add to Cart