ELISA Kit for Rat Thioredoxin-dependent peroxide reductase, mitochondrial

Mfr.No.	E12084r
Alternative Names	PRx III ; Peroxiredoxin-3 ; PRX-3
Categories	Elisa
Function	Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Specificity	Natural and recombinant Rat Thioredoxin-dependent peroxide reductase, mitochondrial
Subcellular Location	Mitochondrion
Detection Range	0.312-20ng/mL
Entryname	PRDX3_RAT
Method Type	Sandwich
Platform	PF10417
Protein Name	Thioredoxin-dependent peroxide reductase, mitochondrial
Sensitivity	0.086ng/mL
Sequence	50: MAAAAGRLLW ; SSVARPASTI ; FRSISASTVL ; RPVASRRTCL ; TDMLWSACPQ ; 100: AKFAFSTSSS ; FHTPAVTQHA ; PHFKGTAVVN ; GEFKELSLDD ; FKGKYLVLFF ; 150: YPLDFTFVCP ; TEIVAFSDKA ; NEFHDVNCEV ; VAVSVDSHFS ; HLAWINTPRK ; 200: NGGLGHMNIT ; LLSDLTKQIS ; RDYGVLLESA ; GIALRGLFII ; DPNGVIKHLS ; 250: VNDLPVGRSV ; EEPLRLVKAF ; QFVETHGEVC ; PANWTPESPT ; IKPSPTASKE ; 257: YFEKVHQ
Sequence Length	257
String	Q9Z0V6
Sub Unit	Dodecameric ring assembled from homodimeric units; disulfide-linked, upon oxidation. The rings have an approximate diameter of 150 A and a central hole of 70 A. 3-5% of the rings are interlocked by pairs. Binds MAP3K13 (By similarity). Interacts with NEK6.

Reference	1. "Cloning of the peroxiredoxin gene family in rats and characterization of the fourth member." Matsumoto A., Okado A., Fujii T., Fujii J., Egashira M., Niikawa N., Taniguchi N. FEBS Lett.443:246-250(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY tissue: Kidney. 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] 3. Lubec G., Afjehi-Sadat L. Submitted (2006-11) to the UniProtKB [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 171-208; 172-197 AND 209-239;IDENTIFICATION BY MASS SPECTROMETRY strain: Sprague-Dawley. tissue: Spinal cord.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808776	E12084r	96T	$796		Add to Cart