ELISA Kit for Rat Sphingosine 1-phosphate receptor 1

Mfr.No.	E1433r
Antigen	S1PR1
Alternative Names	Endothelial differentiation G-protein coupled receptor 1 ; Sphingosine 1-phosphate receptor Edg-1 ; S1P receptor Edg-1 ; CD363 ; Edg1
Categories	Elisa
Function	Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Seems to be coupled to the G(i) subclass of heteromeric G proteins.
Specificity	Natural and recombinant Rat Sphingosine 1-phosphate receptor 1
Subcellular Location	Cell membrane Multi-pass membrane protein
Detection Range	0.312-20ng/mL
Entryname	S1PR1_RAT
Method Type	Sandwich
Platform	PF00001
Protein Name	Sphingosine 1-phosphate receptor 1
Sensitivity	0.192ng/mL
Sequence	50: MVSSTSIPVV ; KALRSQVSDY ; GNYDIIVRHY ; NYTGKLNIGV ; EKDHGIKLTS ; 100: VVFILICCLI ; ILENIFVLLT ; IWKTKKFHRP ; MYYFIGNLAL ; SDLLAGVAYT ; 150: ANLLLSGATT ; YKLTPAQWFL ; REGSMFVALS ; ASVFSLLAIA ; IERYITMLKM ; 200: KLHNGSNSSR ; SFLLISACWV ; ISLILGGLPI ; MGWNCISSLS ; SCSTVLPLYH ; 250: KHYILFCTTV ; FTLLLLSIVI ; LYCRIYSLVR ; TRSRRLTFRK ; NISKASRSSE ; 300: KSLALLKTVI ; IVLSVFIACW ; APLFILLLLD ; VGCKAKTCDI ; LYKAEYFLVL ; 350: AVLNSGTNPI ; IYTLTNKEMR ; RAFIRIISCC ; KCPNGDSAGK ; FKRPIIPGME ; 383: FSRSKSDNSS ; HPQKDDGDNP ; ETIMSSGNVN ; SSS
Sequence Length	383
String	P48303

Reference	1. "Cloning of the rat edg-1 immediate-early gene: expression pattern suggests diverse functions." Lado D.C., Browe C.S., Gaskin A.A., Borden J.M., Maclennan A.J. Gene149:331-336(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];DEVELOPMENTAL STAGE tissue: Cerebellum. 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Placenta.

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