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ELISA Kit for Rat Spectrin alpha chain, brain

SKU : BHE13811012

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0292r
Alternative Names	Alpha-II spectrin ; Fodrin alpha chain ; Spectrin ; non-erythroid alpha chain ; Spna2 ; Spta2
Categories	Elisa
Function	Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Specificity	Natural and recombinant Rat Spectrin alpha chain, brain
Subcellular Location	Cytoplasm cytoskeleton Cytoplasm cell cortex Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells.
Detection Range	0.312-20ng/mL
Entryname	SPTA2_RAT
Method Type	Sandwich
Platform	PF00036
Protein Name	Spectrin alpha chain, brain
Sensitivity	0.181ng/mL
Sequence	50: MDPSGVKVLE ; TAEDIQERRQ ; QVLDRYHRFK ; ELSTLRRQKL ; EDSYRFQFFQ ; 100: RDAEELEKWI ; QEKLQVASDE ; NYKDPTNLQG ; KLQKHQAFEA ; EVQANSGAIV ; 150: KLDETGNLMI ; SEGHFASETI ; RTRLMELHRQ ; WELLLEKMRE ; KGIKLLQAQK ; 200: LVQYLRECED ; VMDWINDKEA ; IVTSEELGQD ; LEHVEVLQKK ; FEEFQTDLAA ; 250: HEERVNEVNQ ; FAAKLIQEQH ; PEEELIKTKQ ; EEVNAAWQRL ; KGLALQRQGK ; 300: LFGAAEVQRF ; NRDVDETIGW ; IKEKEQLMAS ; DDFGRDLASV ; QALLRKHEGL ; 350: ERDLAALEDK ; VKALCAEADR ; LQQSHPLSAN ; QIQVKREELI ; TNWEQIRTLA ; 400: AERHARLDDS ; YRLQRFLADF ; RDLTSWVTEM ; KALINADELA ; NDVAGAEALL ; 450: DRHQEHKGEI ; DAHEDSFKSA ; DESGQALLAA ; GHYASDEVRE ; KLSILSEERA ; 500: ALLELWELRR ; QQYEQCMDLQ ; LFYRDTEQVD ; NWMSKQEAFL ; LNEDLGDSLD ; 550: SVEALLKKHE ; DFEKSLSAQE ; EKITALDEFA ; TKLIQNNHYA ; MEDVATRRDA ; 600: LLSRRNALHE ; RAMHRRAQLA ; DSFHLQQFFR ; DSDELKSWVN ; EKMKTATDEA ; 650: YKDPSNLQGK ; VQKHQAFEAE ; LSANQSRIDA ; LEKAGQKLID ; VNHYAKEEVA ; 700: ARMNEVISLW ; KKLLEATELK ; GVKLREANQQ ; QQFNRNVEDI ; ELWLYEVEGH ; 750: LASDDYGKDL ; TNVQNLQKKH ; ALLEADVAAH ; QDRIDGITIQ ; ARQFQDAGHF ; 800: DAENIKKKQE ; ALVARYEALK ; EPMVARKQKL ; ADSLRLQQLF ; RDVEDEETWI ; 850: REKEPIAAST ; NRGKDLIGVQ ; NLLKKHQALQ ; AEIAGHEPRI ; KAVTQKGNAM ; 900: VEEGHFAAED ; VKAKLSELNQ ; KWEALKAKAS ; QRRQDLEDSL ; QAQQYFADAN ; 950: EAESWMREKE ; PIVGSTDYGK ; DEDSAEALLK ; KHEALMSDLS ; AYGSSIQALR ; 1000: EQAQSCRQQV ; APMDDETGKE ; LVLALYDYQE ; KSPREVTMKK ; GDILTLLNST ; 1050: NKDWWKVEVN ; DRQGFVPAAY ; VKKLDPAQSA ; SRENLLEEQG ; SIALRQGQID ; 1100: NQTRITKEAG ; SVSLRMKQVE ; ELYQSLLELG ; EKRKGMLEKS ; CKKFMLFREA ; 1150: NELQQWINEK ; EAALTSEEVG ; ADLEQVEVLQ ; KKFDDFQKDL ; KANESRLKDI ; 1200: NKVAEDLESE ; GLMAEEVQAV ; QQQEVYGMMP ; RDEADSKTAS ; PWKSARLMVH ; 1250: TVATFNSIKE ; LNERWRSLQQ ; LAEERSQLLG ; SAHEVQRFHR ; DADETKEWIE ; 1300: EKNQALNTDN ; YGHDLASVQA ; LQRKHEGFER ; DLAALGDKVN ; SLGETAQRLI ; 1350: QSHPESAEDL ; KEKCTELNQA ; WTSLGKRADQ ; RKAKLGDSHD ; LQRFLSDFRD ; 1400: LMSWINGIRG ; LVSSDELAKD ; VTGAEALLER ; HQEHRTEIDA ; RAGTFQAFEQ ; 1450: FGQQLLAHGH ; YASPEIKEKL ; DILDQERTDL ; EKAWVQRRMM ; LDHCLELQLF ; 1500: HRDCEQAENW ; MAAREAFLNT ; EDKGDSLDSV ; EALIKKHEDF ; DKAINVQEEK ; 1550: IAALQAFADQ ; LIAVDHYAKG ; DIANRRNEVL ; DRWRRLKAQM ; IEKRSKLGES ; 1600: QTLQQFSRDV ; DEIEAWISEK ; LQTASDESYK ; DPTNIQSKHQ ; KHQAFEAELH ; 1650: ANADRIRGVI ; DMGNSLIERG ; ACAGSEDAVK ; ARLAALADQW ; QFLVQKSAEK ; 1700: SQKLKEANKQ ; QNFNTGIKDF ; DFWLSEVEAL ; LASEDYGKDL ; ASVNNLLKKH ; 1750: QLLEADISAH ; EDRLKDLNSQ ; ADSLMTSSAF ; DTSQVKEKRD ; TINGRFQKIK ; 1800: SMATSRRAKL ; SESHRLHQFF ; RDMDDEESWI ; KEKKLLVSSE ; DYGRDLTGVQ ; 1850: NLRKKHKRLE ; AELAAHEPAI ; QGVLDTGKKL ; SDDNTIGQEE ; IQQRLAQFVE ; 1900: HWKELKQLAA ; ARGQRLEESL ; EYQQFVANVE ; EEEAWINEKM ; TLVASEDYGD ; 1950: TLAAIQGLLK ; KHEAFETDFT ; VHKDRVNDVC ; TNGQDLIKKN ; NHHEENISSK ; 2000: MKGLNGKVSD ; LEKAAAQRKA ; KLDENSAFLQ ; FNWKADVVES ; WIGEKENSLK ; 2050: TDDYGRDLSS ; VQTLLTKQET ; FDAGLQAFQQ ; EGIANITALK ; DQLLAAKHIQ ; 2100: SKAIEARHAS ; LMKRWTQLLA ; NSATRKKKLL ; EAQSHFRKVE ; DLFLTFAKKA ; 2150: SAFNSWFENA ; EEDLTDPVRC ; NSLEEIKALR ; EAHDAFRSSL ; SSAQADFNQL ; 2200: AELDRQIKSF ; RVASNPYTWF ; TMEALEETWR ; NLQKIIKERE ; LELQKEQRRQ ; 2250: EENDKLRQEF ; AQHANAFHQW ; IQETRTYLLD ; GSCMVEESGT ; LESQLEATKR ; 2300: KHQEIRAMRS ; QLKKIEDLGA ; AMEEALILDN ; KYTEHSTVGL ; AQQWDQLDQL ; 2350: GMRMQHNLEQ ; QIQARNTTGV ; TEEALKEFSM ; MFKHFDKDKS ; GRLNHQEFKS ; 2400: CLRSLGYDLP ; MVEEGEPDPE ; FEAILDTVDP ; NRDGHVSLQE ; YMAFMISRET ; 2450: ENVKSSEEIE ; SAFRALSSEG ; KPYVTKEELY ; QNLTREQADY ; CVSHMKPYVD ; 2472: GKGRELPTAF ; DYVEFTRSLF ; VN
Sequence Length	2472
String	P16086
Sub Unit	Like erythrocyte spectrin, the spectrin-like proteins are capable of forming dimers which can further associate to tetramers. Interacts (via C-terminal spectrin repeats) with TRPC4 (By similarity). Interacts with CALM and EMD (By similarity). Interacts with isoform 1 of ACP1. Identified in a complex with ACTN4, CASK, IQGAP1, MAGI2, NPHS1 and SPTBN1.

Uniprot	P16086
Gene Name	Sptan1
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:64159
Unigene	Rn.5812

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BHE13811012	E0292r	96T	$796		Add to Cart

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