May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).
Specificity
Natural and recombinant Rat Solute carrier family 40 member 1
Subcellular Location
Cell membrane Multi-pass membrane protein Localized to the basolateral membrane of polarized epithelial cells.
"Iron induces ferroportin 1 (FPT1) clustering and redistribution in rat intestinal epithelial cells." Yeh K.-Y., Yeh M., Glass J. Submitted (2002-02) to the EMBL/GenBank/DDBJ databases
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