ELISA Kit for Rat Serine/threonine-protein kinase 17B

Mfr.No.	E5498r
Alternative Names	DAP kinase-related apoptosis-inducing protein kinase 2 ; Drak2
Categories	Elisa
Function	Acts as a positive regulator of apoptosis.
Specificity	Natural and recombinant Rat Serine/threonine-protein kinase 17B
Subcellular Location	Nucleus
Detection Range	0.312-20ng/mL
Entryname	ST17B_RAT
Method Type	Sandwich
Platform	PF00069
Protein Name	Serine/threonine-protein kinase 17B
Sensitivity	0.176ng/mL
Sequence	50: MSRRRFDCRS ; ISGLLTTTPQ ; TPMKTENFNN ; FYTLTPKELG ; RGKFAVVRQC ; 100: ISKSTGQEYA ; AKFLKKRRRG ; QDCRAEILHE ; IAVLELARSC ; PHVINLHEVY ; 150: ETATEIILVL ; EYAAGGEIFN ; LCLPELAEMV ; SENDVIRLIK ; QILEGVHYLH ; 200: QNNIVHLDLK ; PQNILLSSIY ; PLGDIKIVDF ; GMSRKIGNAS ; ELREIMGTPE ; 250: YLAPEILNYD ; PITTATDMWN ; IGIIAYMLLT ; HTSPFVGEDN ; QETYLNISQV ; 300: NVDYSEEMFS ; SVSQLATDFI ; QSLLVKNPEK ; RPTAESCLSH ; SWLQQWDFGS ; 350: LFHPEETSES ; SQTQDLSLRS ; SEDKTPKSCN ; GSCGDREDKE ; NIPEDDSLLS ; 371: KRFRFDDSLP ; SPHELVPDLF ; C
Sequence Length	371
String	Q91XS8
Sub Unit	Interacts with CHP causing CHP to translocate from the Golgi to the nucleus.

Reference	1. "A serine/threonine kinase which causes apoptosis-like cell death interacts with a calcineurin B-like protein capable of binding Na+/H+ exchanger." Matsumoto M., Miyake Y., Nagita M., Inoue H., Shitakubo D., Takemoto K., Ohtsuka C., Murakami H., Nakamura N., Kanazawa H. J. Biochem.130:217-225(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INTERACTION WITH CHP1;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;MUTAGENESIS OF LYS-62 tissue: Brain. 2. "The apoptosis-inducing protein kinase DRAK2 is inhibited in a calcium-dependent manner by the calcium-binding protein CHP." Kuwahara H., Kamei J., Nakamura N., Matsumoto M., Inoue H., Kanazawa H. J. Biochem.134:245-250(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS A MYOSIN LIGHT CHAIN KINASE;AUTOPHOSPHORYLATION;MUTAGENESIS OF LYS-62

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