ELISA Kit for Rat Sclerostin domain-containing protein 1

Mfr.No.	E0465r
Alternative Names	Uterine sensitization-associated gene 1 protein ; USAG-1 ; Wnt-signaling modulator ; Usag1 ; Wise
Categories	Elisa
Function	Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner (By similarity). May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction. Enhances Wnt signaling and inhibits TGF-beta signaling.
Specificity	Natural and recombinant Rat Sclerostin domain-containing protein 1
Subcellular Location	Secreted
Detection Range	78-5000pg/mL
Entryname	SOSD1_RAT
Method Type	Sandwich
Platform	PF05463
Protein Name	Sclerostin domain-containing protein 1
Sensitivity	39pg/mL
Sequence	50: MLPPAIHLSL ; IPLLCILMKN ; CLAFKNDATE ; ILYSHVVKPV ; SAHPSSNSTL ; 100: NQARNGGRHF ; SSTGLDRNSR ; VQVGCRELRS ; TKYISDGQCT ; SISPLKELVC ; 150: AGECLPLPVL ; PNWIGGGYGT ; KYWSRRSSQE ; WRCVNDKTRT ; QRIQLQCQDG ; 200: STRTYKITVV ; TACKCKRYTR ; QHNESSHNFE ; SVSPAKPAQH ; HRERKRASKS ; 206: SKHSLS
Sequence Length	206
String	Q642G2
Sub Unit	Interacts with BMP2, BMP4, BMP6 and BMP7 with high affinity.

Reference	1. "Uterine sensitization-associated gene-1: a novel gene induced within the rat endometrium at the time of uterine receptivity/sensitization for the decidual cell reaction." Simmons D.G., Kennedy T.G. Biol. Reprod.67:1638-1645(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;INDUCTION strain: Sprague-Dawley. tissue: Uterus. 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Heart. 3. "The WNT signalling modulator, Wise, is expressed in an interaction-dependent manner during hair-follicle cycling." O'Shaughnessy R.F.L., Yeo W., Gautier J., Jahoda C.A.B., Christiano A.M. J. Invest. Dermatol.123:613-621(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE

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BHE13810618	E0465r	96T	$796		Add to Cart