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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat RISC-loading complex subunit TARBP2

SKU : BHE13811161

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E3425r
Categories	Elisa
Function	Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1.
Specificity	Natural and recombinant Rat RISC-loading complex subunit TARBP2
Subcellular Location	Cytoplasm Cytoplasm perinuclear region Nucleus
Detection Range	0.312-20ng/mL
Entryname	TRBP2_RAT
Method Type	Sandwich
Platform	PF00035
Protein Name	RISC-loading complex subunit TARBP2
Sensitivity	0.157ng/mL
Sequence	50: MSEEDQGSGS ; TTGCGLPSIE ; QMLAANPGKT ; PISLLQEYGT ; RIGKTPVYDL ; 100: LKAEGQAHQP ; NFTFRVTVGD ; TSCTGQGPSK ; KAAKHKAAEV ; ALKHLKGGSM ; 150: LEPALEDSSS ; FSLLDSSVPE ; DTAVIAAEAA ; APVPSALLTR ; SPPMEMQPPV ; 200: SPQQSECNPV ; GALQELVVQK ; GWRLPEYMVT ; QESGPAHRKE ; FTMTCRVERF ; 250: IEIGSGTSKK ; LAKRNAAAKM ; LLRVHTVPLD ; ARDGNEAEPD ; DDHFSIGVSS ; 300: RLDGLRNRGP ; GCTWDSLRNS ; VGEKILSLRN ; CSVGSLGSLG ; SACCSILSEL ; 350: SAEQAFHVSY ; LDIEELSLSG ; LCQCLVELST ; QPATVCYGSA ; TTREAARGDA ; 365: ARRALQYLRI ; MAGSK
Sequence Length	365
String	Q3SWU0
Sub Unit	Self-associates. Component of the RISC loading complex (RLC), or micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Note that the trimeric RLC/miRLC is also referred to as RISC. Interacts with EIF2AK2/PKR and inhibits its protein kinase activity. Interacts with DHX9, EIF6, MOV10 and PRKRA. Associates with the 60S ribosome.

Uniprot	Q3SWU0
Gene Name	Tarbp2
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:363006
Unigene	Rn.17227

Reference	1. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (2005-07) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Kidney.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811161	E3425r	96T	$796		Add to Cart

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