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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Retinoid isomerohydrolase

SKU : BHE13809880

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9829r
Alternative Names	All-trans-retinyl-palmitate hydrolase ; Retinal pigment epithelium-specific 65 kDa protein ; Retinol isomerase
Categories	Elisa
Function	Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.
Specificity	Natural and recombinant Rat Retinoid isomerohydrolase
Subcellular Location	Cytoplasm Cell membrane Lipid-anchor Attached to the membrane by a lipid anchor when palmitoylated (membrane form), soluble when unpalmitoylated.
Detection Range	78-5000pg/mL
Entryname	RPE65_RAT
Method Type	Sandwich
Platform	PF03055
Protein Name	Retinoid isomerohydrolase
Sensitivity	39pg/mL
Sequence	50: MSIQIEHPAG ; GYKKLFETVE ; ELSTPLTAHV ; TGRIPLWLTG ; SLLRCGPGLF ; 100: EVGSEPFYHL ; FDGQALLHKF ; DFKEGHVTYY ; RRFIRTDAYV ; RAMTEKRIVI ; 150: TEFGTCAFPD ; PCKNIFSRFF ; SYFRGVEVTD ; NALVNIYPVG ; EDYYACTETN ; 200: FITKINPETL ; ETIKQVDLCN ; YVSVNGATAH ; PHIESDGTVY ; NIGNCFGKNF ; 250: TVAYNIIKIP ; PLKADKEDPI ; NKSEVVVQFP ; CSDRFKPSYV ; HSFGLTPNYI ; 300: VFVETPVKIN ; LFKFLSSWSL ; WGANYMDCFE ; SNESMGVWLH ; VADKKRRKYF ; 350: NNKYRTSPFN ; LFHHINTYED ; NGFLIVDLCC ; WKGFEFVYNY ; LYLANLRENW ; 400: EEVKRNAMKA ; PQPEVRRYVL ; PLTIDKADTG ; RNLVTLPHTT ; ATAILCSDET ; 450: IWLEPEVLFS ; GPRQAFEFPQ ; INYQKCGGKP ; YTYAYGLGLN ; HFVPDKLCKL ; 500: NVKTKEIWMW ; QEPDSYPSEP ; IFVSQPDALE ; EDDGVVLSVV ; VSPGAGQKPA ; 533: YLLVLNAKDL ; SEIARAEVET ; NIPVTFHGLF ; KKP
Sequence Length	533

Uniprot	O70276
Gene Name	Rpe65
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:89826
Unigene	Rn.76724

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809880	E9829r	96T	$796		Add to Cart

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