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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat RE1-silencing transcription factor

SKU : BHE13809837

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15323r
Alternative Names	Neural-restrictive silencer factor ; Nrsf
Categories	Elisa
Function	Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
Specificity	Natural and recombinant Rat RE1-silencing transcription factor
Subcellular Location	Nucleus
Entryname	REST_RAT
Platform	PF00096
Protein Name	RE1-silencing transcription factor
Sequence	50: MATQVMGQSS ; GGGSLFNNSG ; NMGMALPNDM ; YDLHDLSKAE ; LAAPQLIMLA ; 100: NVALTGEVNG ; SCCDYLVGEE ; RQMAELMPVG ; DNHFSDSEGE ; GLEESAELKG ; 150: DPSGLDNMEL ; RSLELSVVEP ; QPVFEASAAP ; EVYSSNKDPA ; PEAPVAEDKC ; 200: KNLKAKPFRC ; KPCQYEAESE ; EQFVHHIRVH ; SAKKFFVEES ; AEKQAKARES ; 250: GASPSEEGEF ; SKGPIRCDRC ; GYNTNRYDHY ; TAHLKHHLRA ; GDNERVYKCI ; 300: ICTYTTVSEY ; HWRKHLRNHF ; PRKVYTCSKC ; NYFSTEKNNY ; VQHVRTHTGE ; 350: RPYKCELCPY ; SSSQKTHLTR ; HMRTHSGEKP ; FKCDQCNYVA ; SNQHEVTRHA ; 400: RQVHNGPKPL ; NCPHCDYKTA ; DRSNFKKHVE ; LHVNPRQFNC ; PVCDYAASKK ; 450: CNLQYHFKSK ; HPTCPSKTMD ; VSKVKLKKTK ; RREADLHRDA ; AAAATEQTDT ; 500: EQAKTKGVDA ; SARRSERPVK ; GVGKDVPKEK ; KPCSNASVVQ ; VTTRTRKSAV ; 550: ETKAAEGKHT ; DGQTGNNAEK ; SSKAKKSKRK ; MDAEAHPSVE ; PVTEGPVTKK ; 600: KKTESKPKTS ; GEVPKGSRVE ; DRKADKQQSA ; SIKKGGKKTA ; LKTKTAKKGS ; 650: KLAPKWVGHT ; EPSSEMAQGG ; ESPVPALTQA ; VVTPSGSTQT ; ELSSPMDIAQ ; 700: TEPAQMDVSQ ; TGPPQVQRPL ; PVEPAQLEPS ; PPQEPPQVEP ; PACVEPPPPV ; 750: EPPCPMEPAE ; MEPSPPMEPS ; QVEPPPHLEP ; PLPMELPQVE ; LPPVEDCQKE ; 800: LPPVEHAQTK ; VAQTGPTQVG ; AVQEEPLFCL ; RATSSQANQK ; VISPKDRAKE ; 850: KLSVLSEMAR ; QEQVLIEVGL ; VPVRDSQLLK ; ASKSAPDLPA ; PPSPLPKGHL ; 900: RREETPKDQE ; MFSDGEGNKV ; SPLEKGGTEE ; AGESRAELAA ; PMESTSALSS ; 950: EQSSNAPDGE ; TLHSECQADS ; TAVCEMEVDT ; EQKTDRVPLK ; DSAVEPVSPL ; 1000: NPRVDPEAAA ; PAVVASPPIT ; LAESQEIDED ; EGIHSHDGSD ; LSDNMSEGSD ; 1050: DSGLHGARPA ; PQEATSKSGK ; EGLAVKVTEG ; EFVCIFCDRS ; FRKEKDYSKH ; 1069: LNRHLVNVYF ; LEEAAEEQE
Sequence Length	1069
String	O54963
Sub Unit	Interacts with SIN3A, SIN3B and RCOR1.

Uniprot	O54963
Gene Name	Rest
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:83618
Unigene	Rn.10879

Reference	1. "Neuronal expression of zinc finger transcription factor REST/NRSF/XBR gene." Palm K., Belluardo N., Metsis M., Timmusk T. J. Neurosci.18:1280-1296(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2; 3; 4; 5; 6 AND 7);FUNCTION TISSUE SPECIFICITY;INDUCTION;DEVELOPMENTAL STAGE

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809837	E15323r	96T	$796		Add to Cart

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