ELISA Kit for Rat Ras-related protein Rab-14

Mfr.No.	E14990r
Categories	Elisa
Function	Involved in membrane trafficking between the Golgi complex and endosomes during early embryonic development. Regulates the Golgi to endosome transport of FGFR-containing vesicles during early development, a key process for developing basement membrane and epiblast and primitive endoderm lineages during early postimplantation development. May act by modulating the kinesin KIF16B-cargo association to endosomes.
Specificity	Natural and recombinant Rat Ras-related protein Rab-14
Subcellular Location	Early endosome membrane Lipid-anchor Cytoplasmic side Golgi apparatus membrane Lipid-anchor Cytoplasmic side Golgi apparatus trans-Golgi network membrane Lipid-anchor Cytoplasmic side
Detection Range	0.312-20ng/mL
Entryname	RAB14_RAT
Method Type	Sandwich
Platform	PF00071
Protein Name	Ras-related protein Rab-14
Sensitivity	0.08ng/mL
Sequence	50: MATTPYNYSY ; IFKYIIIGDM ; GVGKSCLLHQ ; FTEKKFMADC ; PHTIGVEFGT ; 100: RIIEVSGQKI ; KLQIWDTAGQ ; ERFRAVTRSY ; YRGAAGALMV ; YDITRRSTYN ; 150: HLSSWLTDAR ; NLTNPNTVII ; LIGNKADLEA ; QRDVTYEEAK ; QFAEENGLLF ; 200: LEASAKTGEN ; VEDAFLEAAK ; KIYQNIQDGS ; LDLNAAESGV ; QHKPSAPQGG ; 215: RLTSEPQPQR ; EGCGC
Sequence Length	215
String	P61107
Sub Unit	Interacts with KIF16B. Interacts with ZFYVE20.

Reference	1. "Rab15, a novel low molecular weight GTP-binding protein specifically expressed in rat brain." Elferink L.A., Anzai K., Scheller R.H. J. Biol. Chem.267:5768-5775(1992) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Sprague-Dawley. tissue: Brain. 2. "Rab14 is involved in membrane trafficking between the Golgi complex and endosomes." Junutula J.R., De Maziere A.M., Peden A.A., Ervin K.E., Advani R.J., van Dijk S.M., Klumperman J., Scheller R.H. Mol. Biol. Cell15:2218-2229(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;MUTAGENESIS OF SER-25; GLN-70 AND ASN-124

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809351	E14990r	96T	$796		Add to Cart