ELISA Kit for Rat Protein S100-A6

Mfr.No.	E1769r
Alternative Names	Calcyclin ; Prolactin receptor-associated protein ; S100 calcium-binding protein A6 ; Cacy
Categories	Elisa
Function	May function as calcium sensor and contribute to cellular calcium signaling (Potential). May function by interacting with other proteins and indirectly play a role in the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative (By similarity). Interacts with FKBP4.
Specificity	Natural and recombinant Rat Protein S100-A6
Subcellular Location	Nucleus envelope Cytoplasm Cell membrane Peripheral membrane protein Cytoplasmic side
Detection Range	0.78-50ng/mL
Entryname	S10A6_RAT
Method Type	Sandwich
Platform	PF01023
Protein Name	Protein S100-A6
Sensitivity	0.419ng/mL
Sequence	50: MACPLDQAIG ; LLVAIFHKYS ; GKEGDKHTLS ; KKELKELIQK ; ELTIGAKLQD ; 89: AEIARLMDDL ; DRNKDQEVNF ; QEYVAFLGAL ; ALIYNEALK
Sequence Length	89
String	P05964
Sub Unit	Homodimer; head to tail assembly of 2 subunits. Interacts with ANXA2 and ANXA11 (via N-terminus). Interacts with SUGT1 and CACYBP. Interacts with TP53. Interacts with tropomyosin.

Reference	1. "Cloning and characterization of a cDNA encoding a highly conserved, putative calcium binding protein, identified by an anti-prolactin receptor antiserum." Murphy L.C., Murphy L.J., Tsuyuki D., Duckworth M.L., Shiu R.P.C. J. Biol. Chem.263:2397-2401(1988) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Calcyclin is differentially expressed in rat testicular cells." Konrad L., Aumueller G. Biochim. Biophys. Acta1489:440-444(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Wistar. 3. Kizawa K. Submitted (1999-04) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Wistar. 4. Lubec G., Kang S.U., Lubec S. Submitted (2007-09) to the UniProtKB [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 48-55;IDENTIFICATION BY MASS SPECTROMETRY strain: Sprague-Dawley. tissue: Brain.

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