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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Prostaglandin-H2 D-isomerase

SKU : BHE13809685

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0167r
Alternative Names	Glutathione-independent PGD synthase ; Lipocalin-type prostaglandin-D synthase ; Prostaglandin-D2 synthase ; PGD2 synthase
Categories	Elisa
Function	Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.
Specificity	Natural and recombinant Rat Prostaglandin-H2 D-isomerase
Subcellular Location	Rough endoplasmic reticulum Nucleus membrane Golgi apparatus Cytoplasm perinuclear region Secreted Detected on rough endoplasmic reticulum of arachnoid and menigioma cells. Localized to the nuclear envelope, Golgi apparatus, secretory vesicles and spherical cytoplasmic structures in arachnoid trabecular cells, and to circular cytoplasmic structures in meningeal macrophages and perivascular microglial cells. In oligodendrocytes, localized to the rough endoplasmic reticulum and nuclear envelope. In retinal pigment epithelial cells, localized to distinct cytoplasmic domains including the perinuclear region. Also secreted.
Detection Range	0.156-10ng/ml
Entryname	PTGDS_RAT
Method Type	Sandwich
Platform	PF00061
Protein Name	Prostaglandin-H2 D-isomerase
Sensitivity	0.084ng/mL
Sequence	50: MAALPMLWTG ; LVLLGLLGFP ; QTPAQGHDTV ; QPNFQQDKFL ; GRWYSAGLAS ; 100: NSSWFREKKE ; LLFMCQTVVA ; PSTEGGLNLT ; STFLRKNQCE ; TKVMVLQPAG ; 150: VPGQYTYNSP ; HWGSFHSLSV ; VETDYDEYAF ; LFSKGTKGPG ; QDFRMATLYS ; 189: RAQLLKEELK ; EKFITFSKDQ ; GLTEEDIVFL ; PQPDKCIQE
Sequence Length	189
String	P22057
Sub Unit	Monomer.

Uniprot	P22057
Gene Name	Ptgds
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:25526
Unigene	Rn.11400

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SKU	Supplier No.	Size	Your price	Quantity
BHE13809685	E0167r	96T	$796		Add to Cart

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