ELISA Kit for Rat Prostaglandin D2 receptor

Mfr.No.	E15002r
Alternative Names	Prostanoid DP receptor
Categories	Elisa
Function	Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate.
Specificity	Natural and recombinant Rat Prostaglandin D2 receptor
Subcellular Location	Cell membrane Multi-pass membrane protein
Detection Range	0.78-50ng/mL
Entryname	PD2R_RAT
Method Type	Sandwich
Platform	PF00001
Protein Name	Prostaglandin D2 receptor
Sensitivity	0.33ng/mL
Sequence	50: MNESYRCQAA ; TWVERGSSAT ; MGGVAFSAGL ; LGNLLALVLL ; ARSGLGSCRP ; 100: GPLHPPPSVF ; YVLVCGLTVT ; DLLGKCLISP ; MVLAAYAQNR ; SLKELLPASG ; 150: NQLCEAFAFL ; MSFFGLASTL ; QLLAMALECW ; LSLGHPFFYQ ; RHITARRGVL ; 200: VAPVAGAFSL ; AFCALPFAGF ; GKFVQYCPGT ; WCFIQMIHKK ; RSFSVIGFSV ; 250: LYSSLMALLV ; LATVVCNLGA ; MSNLYAMHRR ; QRHHPRRCSR ; DRAQSGSDYR ; 300: HGSPNPLEEL ; DHFVLLALTT ; VLFTMCSLPL ; IYRAYYGAFK ; LVDRADGDSE ; 350: DLQALRFLSV ; ISIVDPWIFI ; IFRTSVFRML ; FHKTFTRPLI ; YRNWCSHSWQ ; 357: TNMESTL
Sequence Length	357
String	Q9R261

Reference	1. "A novel biological role for prostaglandin D2 is suggested by distribution studies of the rat DP prostanoid receptor." Wright D.H., Nantel F., Metters K.M., Ford-Hutchinson A.W. Eur. J. Pharmacol.377:101-115(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY strain: Sprague-Dawley. 2. "Pharmacological and cardiovascular properties of a hydantoin derivative, BW 245 C, with high affinity and selectivity for PGD2 receptors." Town M.H., Casals-Stenzel J., Schillinger E. Prostaglandins25:13-28(1983) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

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BHE13808104	E15002r	96T	$796		Add to Cart