ELISA Kit for Rat Platelet-activating factor acetylhydrolase 2, cytoplasmic

Mfr.No.	E1487r
Alternative Names	Serine-dependent phospholipase A2 ; SD-PLA2
Categories	Elisa
Function	Catalyzes transacetylation of the acetyl group from platelet-activating factor (PAF) to lysoplasmalogen and to sphingosine, producing plasmalogen analogs of PAF and N-acetylsphingosine (C2-ceramide) respectively. Also acts as a PAF-acetylhydrolase in the absence of lipid acceptor molecules.
Specificity	Natural and recombinant Rat Platelet-activating factor acetylhydrolase 2, cytoplasmic
Subcellular Location	Cytoplasm
Detection Range	0.312-20ng/mL
Entryname	PAFA2_RAT
Method Type	Sandwich
Platform	PF03403
Protein Name	Platelet-activating factor acetylhydrolase 2, cytoplasmic
Sensitivity	0.156ng/mL
Sequence	50: MGAGQSICFP ; PISGPHHIGC ; TDVMEGHSLE ; GSLFRLFYPC ; EASETCEQPL ; 100: WIPRYEYCVG ; LADYLQYNKR ; WVGLLFNVGI ; GSCRLPVSWN ; GPFKTKESGY ; 150: PLIILSHGLG ; GFRVSYSAFC ; MELASRGFVV ; AAIEHRDQSA ; AATYFCKQTS ; 200: QESSPTESLE ; EEWIPFRRIK ; EGEKEFHVRN ; PQVHQRAKEC ; VRVLQILQDA ; 250: SAGKPVINVF ; PGGLDLMTLK ; GSIDMSRVAV ; MGHSFGGATA ; ILALTQEAQF ; 300: RCAIALDAWM ; FPLEHDFYPK ; ARGPVFFINV ; EKFQTVESVN ; LMKKICAQHE ; 350: QSRIVTVLGA ; VHRSQTDFAF ; VTGNMIGKLF ; SSGTRGTLDP ; YEGQEVMVRA ; 390: MLAFLQKHLD ; LKEDYDQWNS ; FIEGIGPSLI ; QGAPHYLSSL ;
Sequence Length	390
String	P83006
Sub Unit	Monomer.

Reference	1. "Kinetics of platelet-activating factor binding, internalization, degradation, and apoptotic signaling in neural precursors." Bonin F., Moffat T.C., Renaud N., Franks D.J., Bennett S.A.L. Submitted (2003-01) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Wistar. tissue: Brain. 2. "Purification and characterization from rat kidney membranes of a novel platelet-activating factor (PAF)-dependent transacetylase that catalyzes the hydrolysis of PAF, formation of PAF analogs, and C2-ceramide." Karasawa K., Qiu X., Lee T.-C. J. Biol. Chem.274:8655-8661(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 84-96; 169-179 AND 329-357 strain: Sprague-Dawley. tissue: Kidney.

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