Clathrin assembly lymphoid myeloid leukemia protein ; rCALM ; Calm
Categories
Elisa
Function
Assembly protein recruiting clathrin and adapter protein complex 2 (AP2) to cell membranes at sites of coated-pit formation and clathrin-vesicle assembly. May be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. Involved in AP2-dependent clathrin-mediated endocytosis at the neuromuscular junction.
Specificity
Natural and recombinant Rat Phosphatidylinositol-binding clathrin assembly protein
Subcellular Location
Membrane Clathrin-coated pit Golgi apparatus Cytoplasmic vesicle Clathrin-coated vesicle Nucleus Colocalized with clathrin in the Golgi area (By similarity). Interaction with FAM64A may target PICALM to the nucleus in some cells.
Binds clathrin and phosphatidylinositol 4,5-bisphosphate. Interacts with FAM64A; this interaction may change the subcellular location into the nucleus.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY
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Reviews of ELISA Kit for Rat Phosphatidylinositol-binding clathrin assembly protein