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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Nuclear receptor coactivator 3

SKU : BHE13808078

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11290r
Alternative Names	Amplified in breast cancer-1 protein homolog ; AIB-1 ; Aib1
Categories	Elisa
Function	Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, probably via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.
Specificity	Natural and recombinant Rat Nuclear receptor coactivator 3
Subcellular Location	Cytoplasm Nucleus Mainly cytoplasmic and weakly nuclear. Upon TNF activation and subsequent phosphorylation, it translocates from the cytoplasm to the nucleus.
Entryname	NCOA3_RAT
Platform	PF07469
Protein Name	Nuclear receptor coactivator 3
Sequence	50: IIRRCIQRFF ; SLNDGQSWSQ ; KRHYQEAYIH ; GHAETPVYRF ; SLADGTIVSA ; 100: QTKSKLFRNP ; VTNDRHGFVS ; THFLQREQNG ; CRPNPILQDK ; GIRPPAAGCG ; 150: MSLSPSQSVQ ; MLGSRTYGVA ; DPSNTGQMAG ; ARYGASSSVA ; SLTPGQSLQS ; 200: PSSYQSNSYG ; LNMSSPPHGS ; PGLGPNQQNI ; MISPRNRGSP ; KMASHQFSPA ; 250: AGVHSPMGSS ; GNTGSHSFSS ; SSLSALQAIS ; EGVGTSLLST ; LSSPGPKLDN ; 300: SPNMNINQPS ; KASSQDSKSP ; LGLYCEQNPV ; ESSVCPSNSR ; DPPVTKENKE ; 350: NSGEASETPR ; GPLESKGHKK ; LLQLLTCSSD ; DRGHSSLTNS ; PLDSNCKDSS ; 400: ISVTSPSGVS ; SSTSGAVSST ; SNMHGSLLQE ; KHRILHKLLQ ; NGNSPAEVAK ; 450: ITAEATGKDT ; SSTASGGEGS ; VXQEQLSPXK ; KENNALLRYL ; LDRDDPSDVL ; 500: AKELQPQADG ; GDSKLSQCSC ; XTNPSSGQEK ; DPKIKTEEVS ; GDLDNLDAIL ; 550: GDLTSSDFYN ; SPTNGSHPGA ; KQQMFAGPSS ; LGLRSPQPVQ ; SVRPPYNRAL ; 600: SLDSPVSVGS ; VPPVKNVSAF ; PVLPKQPILA ; GNPRMMDSQE ; NYGANMGGPN ; 650: RNVPVNPTSS ; SGDWGLANSR ; ASRMEPLASS ; PLGRAGGDYS ; AALPRPALGS ; 700: SGPTLPLRSN ; RLPGARPTLM ; LQMRAGEVPM ; GMGVSPYSPA ; VPSNQPGSWP ; 750: EGMLSMEQGP ; HGAQNRPLLR ; NSLDELLGPP ; SNPEGQSDER ; ALLDQLHTLL ; 800: SNTDATGLEE ; IDRALGIPEL ; VSQGQALESK ; QDVFQGQEAA ; VMMDQKAALY ; 850: GQTYPAQGPP ; LQGGFHLQGQ ; SPSLNSMMSQ ; ISQQGSFPLQ ; GLHPRASMVR ; 900: PRTNTPKQLR ; MQLQQRLQGQ ; QFLNQSRQAL ; EMKMESPTGA ; AVMRPMLQSQ ; 950: QAFFNAQMAA ; QQKRELMNHH ; LQQQRMAMMM ; SQPQPQAFSP ; PPNVTASPSM ; 1000: DGVLAGSAMP ; QAPPQQFPYA ; TNYGMGQPPE ; PAFGRGSSPP ; SAMMSSRMGP ; 1050: SQNAMVQHPQ ; TAPMYQSSEM ; KGWPSGNLAR ; NGSFPQQQFA ; PQANPAAYNM ; 1082: VHMNSSGSHL ; GQMTMTPMPM ; SGMPMGPDQK ; YC
Sequence Length	1082
String	Q9EPU2
Sub Unit	Present in a complex containing NCOA2, IKKA, IKKB, IKBKG and the histone acetyltransferase protein CREBBP. Interacts with PCAF and CARM1. Interacts with CASP8AP2 and NR3C1 (By similarity). Interacts with ATAD2 and this interaction is enhanced by estradiol (By similarity). Interacts with PSMB9.

Uniprot	Q9EPU2
Gene Name	Ncoa3
Immunogen Species	Rattus norvegicus (Rat)
Unigene	Rn.20691

Reference	1. "Expression of estrogen receptor coactivators in the rat uterus." Nephew K.P., Ray S., Hlaing M., Ahluwalia A., Wu S.D., Long X., Hyder S.M., Bigsby R.M. Biol. Reprod.63:361-367(2000) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY strain: Sprague-Dawley.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808078	E11290r	96T	$796		Add to Cart

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