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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Neuropilin-1

SKU : BHE13808344

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1843r
Alternative Names	Vascular endothelial cell growth factor 165 receptor ; CD304
Categories	Elisa
Function	Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, the PLGF-2 isoform of PGF, the VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis.
Specificity	Natural and recombinant Rat Neuropilin-1
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	15.6-1000pg/mL
Entryname	NRP1_RAT
Method Type	Sandwich
Platform	PF00431
Protein Name	Neuropilin-1
Sensitivity	7.96pg/mL
Sequence	50: MERGLPLLCA ; TLALALALAG ; AFRSDKCGGT ; IKIENPGYLT ; SPGYPHSYHP ; 100: SEKCEWLIQA ; PEPYQRIMIN ; FNPHFDLEDR ; DCKYDYVEVI ; DGENEGGRLW ; 150: GKFCGKIAPS ; PVVSSGPFLF ; IKFVSDYETH ; GAGFSIRYEI ; FKRGPECSQN ; 200: YTAPTGVIKS ; PGFPEKYPNS ; LECTYIIFAP ; KMSEIILEFE ; SFDLEQDSNP ; 250: PGGVFCRYDR ; LEIWDGFPEV ; GPHIGRYCGQ ; KTPGRIRSSS ; GILSMVFYTD ; 300: SAIAKEGFSA ; NYSVLQSSIS ; EDFKCMEALG ; MESGEIHSDQ ; ITASSQYGTN ; 350: WSVERSRLNY ; PENGWTPGED ; SYREWIQVDL ; GLLRFVTAVG ; TQGAISKETK ; 400: KKYYVKTYRV ; DISSNGEDWI ; TLKEGNKAII ; FQGNTNPTDV ; VFGVFPKPLI ; 450: TRFVRIKPAS ; WETGISMRFE ; VYGCKITDYP ; CSGMLGMVSG ; LISDSQITAS ; 500: NQGDRNWMPE ; NIRLVTSRTG ; WALPPSPHPY ; INEWLQVDLG ; DEKIVRGVII ; 550: QGGKHRENKV ; FMRKFKIAYS ; NNGSDWKMIM ; DDSKRKAKSF ; EGNNNYDTPE ; 600: LRAFTPLSTR ; FIRIYPERAT ; HSGLGLRMEL ; LGCEVEVPTA ; GPTTPNGNPV ; 650: DECDDDQANC ; HSGTGDDFQL ; TGGTTVLATE ; KPTIIDSTIQ ; SEFPTYGFNC ; 700: EFGWGSHKTF ; CHWEHDSHAQ ; LRWRVLTSKT ; GPIQDHTGDG ; NFIYSQADEN ; 750: QKGKVARLVS ; PVVYSQSSAH ; CMTFWYHMSG ; SHVGTLRVKL ; HYQKPEEYDQ ; 800: LVWMVVGHQG ; DHWKEGRVLL ; HKSLKLYQVI ; FEGEIGKGNL ; GGIAVDDISI ; 850: NNHIPQEDCA ; KPTDLDKKNT ; EIKIDETGST ; PGYEEGKGDK ; NISRKPGNVL ; 900: KTLDPILITI ; IAMSALGVLL ; GAVCGVVLYC ; ACWHNGMSER ; NLSALENYNF ; 922: ELVDGVKLKK ; DKLNPQSNYS ; EA
Sequence Length	922
String	Q9QWJ9
Sub Unit	Homodimer, and heterodimer with NRP2. Binds PLXNB1.

Uniprot	Q9QWJ9
Gene Name	Nrp1
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:246331
Unigene	Rn.10815

Reference	1. "Neuropilin is a semaphorin III receptor." Kolodkin A.L., Levengood D.V., Rowe E.G., Tai Y.-T., Giger R.J., Ginty D.D. Cell90:753-762(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Sprague-Dawley. 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Kidney. 3. "Structural basis for ligand and heparin binding to neuropilin B domains." Vander Kooi C.W., Jusino M.A., Perman B., Neau D.B., Bellamy H.D., Leahy D.J. Proc. Natl. Acad. Sci. U.S.A.104:6152-6157(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.15 ANGSTROMS) OF 273-586 IN COMPLEX WITH VEGF FRAGMENT;HEPARIN-BINDING;DISULFIDE BONDS

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BHE13808344	E1843r	96T	$796		Add to Cart

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