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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Netrin receptor UNC5C

SKU : BHE13811225

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E7813r
Alternative Names	Protein unc-5 homolog 3 ; Protein unc-5 homolog C ; Unc5h3
Categories	Elisa
Function	Receptor for netrin required for axon guidance. Mediates axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. Also involved in corticospinal tract axon guidances independently of DCC. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
Specificity	Natural and recombinant Rat Netrin receptor UNC5C
Subcellular Location	Membrane Single-pass type I membrane protein
Entryname	UNC5C_RAT
Method Type	Sandwich
Platform	PF00531
Protein Name	Netrin receptor UNC5C
Sequence	50: MRKGLRATAA ; RCGLGLGYLL ; QMLVLPALAL ; LSASGTGSAA ; QDDDFFHELP ; 100: ETFPSDPPEP ; LPHFLIEPEE ; AYIVKNKPVN ; LYCKASPATQ ; IYFKCNSEWV ; 150: HQKDHVVDER ; VDETSGLIVR ; EVSIEISRQQ ; VEELFGPEDY ; WCQCVAWSSA ; 200: GTTKSRKAYV ; RIAYLRKTFE ; QEPLGKEVSL ; EQEVLLQCRP ; PEGIPMAEVE ; 250: WLKNEDIIDP ; VEDRNFYITI ; DHNLIIKQAR ; LSDTANYTCV ; AKNIVAKRKS ; 300: TTATVIVYVN ; GGWSTWAEWS ; VCNSRCGRGY ; QKRTRTCTNP ; APLNGGAFCE ; 350: GQSVQKIACT ; TLCPVDGRWT ; SWSKWSTCGT ; ECTHWRRREC ; TAPAPKNGGK ; 400: DCDGLVLQSK ; NCTDGLCMQA ; APDSDDVALY ; VGIVIAVTVC ; LAITVVVALF ; 450: VYRKNHRDFE ; SNIIDSSALN ; GGFQPVNIKA ; ARQDLLAVPP ; DLTSAAAMYR ; 500: GPVYALHDVS ; DKIPMTNSPI ; LDPLPNLKIK ; VYNSSGAVTP ; QDDLAEFSSK ; 550: LSPQMTQSLL ; ENEALNLKNQ ; SLARQTDPSC ; TAFGTFNSLG ; GHLIIPNSGV ; 600: SLLIPAGAIP ; QGRVYEMYVT ; VHRKENMRPP ; MEDSQTLLTP ; VVSCGPPGAL ; 650: LTRPVILTLH ; HCADPNTEDW ; KIQLKNQAVQ ; GQWEDVVVVG ; EENFTTPCYI ; 700: QLDAEACHIL ; TENLSTYALV ; GQSTTKAAAK ; RLKLAIFGPL ; CCSSLEYSIR ; 750: VYCLDDTQDA ; LKEVLQLERQ ; MGGQLLEEPK ; ALHFKGSIHN ; LRLSIHDITH ; 800: SLWKSKLLAK ; YQEIPFYHIW ; SGSQRNLHCT ; FTLERLSLNT ; VELVCKLCVR ; 850: QVEGEGQIFQ ; LNCTVSEEPT ; GIDLPLLDPA ; STITTVTGPS ; AFSIPLPIRQ ; 900: KLCSSLDAPQ ; TRGHDWRMLA ; HKLNLDRYLN ; YFATKSSPTG ; VILDLWEAQN ; 931: FPDGNLSMLA ; AVLEEMGRHE ; TVVSLAAEGQ ; Y
Sequence Length	931
String	Q761X5
Sub Unit	Interacts with the cytoplasmic part of DCC.

Uniprot	Q761X5
Gene Name	Unc5c
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:362049
Unigene	Rn.47255

Reference	1. "Rat neurological mutations cerebellar vermis defect and hobble are caused by mutations in the netrin-1 receptor gene Unc5h3." Kuramoto T., Kuwamura M., Serikawa T. Brain Res. Mol. Brain Res.122:103-108(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];DISEASE 2. "Netrin-1 acts as a survival factor via its receptors UNC5H and DCC." Llambi F., Causeret F., Bloch-Gallego E., Mehlen P. EMBO J.20:2715-2722(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811225	E7813r	96T	$796		Add to Cart

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