ELISA Kit for Rat N-glycosylase/DNA lyase

Mfr.No.	E1437r
Alternative Names	Mmh ; Ogh1
Categories	Elisa
Function	DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
Specificity	Natural and recombinant Rat N-glycosylase/DNA lyase
Subcellular Location	Nucleus nucleoplasm Nucleus speckle Nucleus matrix Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells.
Detection Range	0.156-10ng/mL
Entryname	OGG1_RAT
Method Type	Sandwich
Platform	PF00730
Protein Name	N-glycosylase/DNA lyase
Sensitivity	0.078ng/mL
Sequence	50: MLFSSSLSSS ; MRHRTLTSSP ; ALWASIPCPR ; SELRLDLVLA ; SGQSFRWREQ ; 100: SPAHWSGVLA ; DQVWTLTQTE ; DQLYCTVYRG ; DKGQVGRPTL ; EELETLHKYF ; 150: QLDVSLTQLY ; SHWASVDSHF ; QSVAQKFQGV ; RLLRQDPTEC ; LFSFICSSNN ; 200: NIARITGMVE ; RLCQAFGPRL ; VQLDDVTYHG ; FPNLHALAGP ; EVETHLRKLG ; 250: LGYRARYVCA ; SAKAILEEQG ; GPAWLQQLRV ; ASYEEAHKAL ; CTLPGVGTKV ; 300: ADCICLMALD ; KPQAVPVDIH ; VWQIAHRDYG ; WQPKTSQTKG ; PSPLANKELG ; 345: NFFRNLWGPY ; AGWAQAVLFS ; ADLRQQNLSR ; EPPAKRKKGS ; KKTEG
Sequence Length	345
String	O70249

Reference	1. "Rat 7,8-dihydro-8-oxoguanine DNA glycosylase: substrate specificity, kinetics and cleavagemechanism at an apurinic site." Prieto Alamo M.J., Jurado J., Francastel E., Laval F. Nucleic Acids Res.26:5199-5202(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Hepatoma.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13808600	E1437r	96T	$796		Add to Cart