ELISA Kit for Rat Intestinal-type alkaline phosphatase 1

Mfr.No.	E0233r
Alternative Names	Intestinal alkaline phosphatase I ; IAP-I
Categories	Elisa
Specificity	Natural and recombinant Rat Intestinal-type alkaline phosphatase 1
Subcellular Location	Cell membrane Lipid-anchor GPI-anchor
Detection Range	1.56-100ng/mL
Entryname	PPBI1_RAT
Method Type	Sandwich
Platform	PF00245
Protein Name	Intestinal-type alkaline phosphatase 1
Sensitivity	0.88ng/mL
Sequence	50: MQGDWVLLLL ; LGLRIHLSFG ; VIPVEEENPV ; FWNQKAKEAL ; DVAKKLQPIQ ; 100: TSAKNLILFL ; GDGMGVPTVT ; ATRILKGQLG ; GHLGPETPLA ; MDHFPFTALS ; 150: KTYNVDRQVP ; DSAGTATAYL ; CGVKANYKTI ; GVSAAARFNQ ; CNSTFGNEVF ; 200: SVMHRAKKAG ; KSVGVVTTTR ; VQHASPAGTY ; AHTVNRDWYS ; DADMPSSALQ ; 250: EGCKDIATQL ; ISNMDIDVIL ; GGGRKFMFPK ; GTPDPEYPGD ; SDQSGVRLDS ; 300: RNLVEEWLAK ; YQGTRYVWNR ; EQLMQASQDP ; AVTRLMGLFE ; PTEMKYDVNR ; 350: NASADPSLAE ; MTEVAVRLLS ; RNPQGFYLFV ; EGGRIDQGHH ; AGTAYLALTE ; 400: AVMFDSAIEK ; ASQLTNEKDT ; LTLITADHSH ; VFAFGGYTLR ; GTSIFGLAPL ; 450: NAQDGKSYTS ; ILYGNGPGYV ; LNSGNRPNVT ; DAESGDVNYK ; QQAAVPLSSE ; 500: THGGEDVAIF ; ARGPQAHLVH ; GVQEQNYIAH ; VMAFAGCLEP ; YTDCGLAPPA ; 540: DENRPTTPVQ ; NSAITMNNVL ; LSLQLLVSML ; LLVGTALVVS ;
Sequence Length	540
String	P15693
Sub Unit	Homodimer.

Reference	1. "Molecular cloning and expression of a cDNA encoding the membrane-associated rat intestinal alkaline phosphatase." Lowe M., Strauss A.W., Alpers R., Seetharam S., Alpers D.H. Biochim. Biophys. Acta1037:170-177(1990) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 21-34 AND 287-300;CATALYTIC ACTIVITY;SUBCELLULAR LOCATION 2. "Two rat intestinal alkaline phosphatase isoforms with different carboxyl-terminal peptides are both membrane-bound by a glycan phosphatidylinositol linkage." Engle M.J., Mahmood A., Alpers D.H. J. Biol. Chem.270:11935-11940(1995) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GPI-ANCHOR 3. "Crystal structure of rat intestinal alkaline phosphatase - Role of crown domain in mammalian alkaline phosphatases." Ghosh K., Mazumder Tagore D., Anumula R., Lakshmaiah B., Kumar P.P., Singaram S., Matan T., Kallipatti S., Selvam S., Krishnamurthy P., Ramarao M. J. Struct. Biol.184:182-192(2013) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.21 ANGSTROMS) OF 21-502 IN COMPLEX WITH MAGNESIUM AND ZINC;GLYCOSYLATION AT ASN-301 AND ASN-428;DISULFIDE BOND;COFACTOR;CATALYTIC ACTIVITY;SUBUNIT;ACTIVE SITE

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