ELISA Kit for Rat Interleukin-6 receptor subunit alpha

Mfr.No.	E1815r
Alternative Names	IL-6R 1 ; CD126 ; Il6ra
Categories	Elisa
Function	Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis.
Specificity	Natural and recombinant Rat Interleukin-6 receptor subunit alpha
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	62.5-4000pg/mL
Entryname	IL6RA_RAT
Method Type	Sandwich
Platform	PF00047
Protein Name	Interleukin-6 receptor subunit alpha
Sensitivity	31.32pg/mL
Sequence	50: MLAVGCTLLV ; ALLAAPAVAL ; VLGSCRALEV ; ANGTVTSLPG ; ATVTLICPGK ; 100: EAAGNATIHW ; VYSGSQSREW ; TTTGNTLVLR ; AVQVNDTGHY ; LCFLDDHLVG ; 150: TVPLLVDVPP ; EEPKLSCFRK ; NPLVNAFCEW ; HPSSTPSPTT ; KAVMFAKKIN ; 200: TTNGKSDFQV ; PCQYSQQLKS ; FSCEVEILEG ; DKVYHIVSLC ; VANSVGSRSS ; 250: HNVVFQSLKM ; VQPDPPANLV ; VSAIPGXPRW ; LKVSWQDPES ; WDPSYYLLQF ; 300: ELRYRPVWSK ; XFTVWPLQVA ; QHQCVIHDAL ; RGVKHVVQVR ; GKEEFDIGQW ; 350: SKWSPEVTGT ; PWLAEPRTTP ; AGIPGNPTQV ; SVEDYDNHED ; QYGSSTEATS ; 400: VLAPVQGSSP ; IPLPTFLVAG ; GSLAFGLLLC ; VFIILRLKKK ; WKSQAEKESK ; 450: TTSPPPYPLG ; PLKPTFLLVP ; LLTPSGSHNS ; SGTDNTGSHS ; CLGVRDPQCP ; 462: NDNSNRDYLF ; PR
Sequence Length	462
String	P22273
Sub Unit	Hexamer of two molecules each of IL6, IL6R and IL6ST.

Reference	1. "Molecular cloning, characterization and functional expression of the rat liver interleukin 6 receptor." Baumann M., Baumann H., Fey G.H. J. Biol. Chem.265:19853-19862(1990) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Fischer 344. tissue: Liver. 2. Gibson T. [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF PROBABLE FRAMESHIFT IN 227-261

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