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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Hypoxia-inducible factor 3-alpha

SKU : BHE13805366

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E10271r
Alternative Names	HIF3-alpha-1
Categories	Elisa
Function	Involved in adaptive response to hypoxia. Suppresses hypoxia-inducible expression of HIF1A and EPAS1. Binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. The complex HIF3A-ARNT activates the transcription of reporter genes driven by HRE.
Specificity	Natural and recombinant Rat Hypoxia-inducible factor 3-alpha
Subcellular Location	Nucleus Cytoplasm In the nuclei of all periportal and perivenous hepatocytes. In the distal perivenous zone, detected in the cytoplasm of the hepatocytes.
Detection Range	15.6-1000pg/mL
Entryname	HIF3A_RAT
Method Type	Sandwich
Platform	PF11413
Protein Name	Hypoxia-inducible factor 3-alpha
Sensitivity	7.98pg/mL
Sequence	50: MDWDQDRSST ; ELRKEKSRDA ; ARSRRSQETE ; VLYQLAHTLP ; FARGVSAHLD ; 100: KASIMRLTIS ; YLRMHRLCAA ; GEWNQVRKEG ; EPLDACYLKA ; LEGFVMVLTA ; 150: EGDMAYLSEN ; VSKHLGLSQL ; ELIGHSIFDF ; IHPCDQEELQ ; DALTPRPSLS ; 200: KKKSEAATGR ; HFSLRMKSTL ; TSRGRALNLK ; AATWKVLHCS ; GHMRAYKPPA ; 250: QTSPAGSPRS ; EPPLQCLVLI ; CEAIPHPASL ; EPPLGRGAFL ; SRHSLDMKFT ; 300: YCDERIAEVA ; GYSPDDLIGC ; SAYEYIHALD ; SDAVSRSIHT ; LLSKGQAVTG ; 350: QYRFLARTGG ; YLWTQTQATV ; VSGGRGPQSE ; SIICVHFLIS ; RVEENGVVLS ; 400: LEQTEQHTRR ; PPQLGTSSKK ; GIPGNSLDPP ; APRILAFLHP ; PALSEASLAA ; 450: DPRRFCSPDL ; RRLMAPILDG ; PPTAATPSTP ; QAARRPQSPL ; PADLPDQLAV ; 500: GLENAHRLST ; ARKNKTMETD ; LDIAQDPDTP ; DLEMLAPYIS ; MDDDFQLNSS ; 550: EQLPKVHRRP ; PRTARRPRAR ; SFHGLSPPIP ; EATLLPRWGS ; DPRLNCSSPS ; 600: KGDPPTAPLT ; PRTRKRALAQ ; SSEDKGLELL ; ETKPPKRSPR ; LEPGSVLLPP ; 650: LSLSFLLQGR ; QLPGNQPDPR ; APLVDSHEPL ; GLAPSLLSLY ; QHEETIQSRN ; 662: HFLPAAGLAQ ; TH
Sequence Length	662
String	Q9JHS2
Sub Unit	Heterodimerizes with ARNT. Interacts via the oxygen-dependent degradation domain (ODD) with the beta domain of VHL.

Uniprot	Q9JHS2
Gene Name	Hif3a
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:64345
Unigene	Rn.161814

Reference	1. "Perivenous expression of the mRNA of the three hypoxia-inducible factor a-subunits HIF-1a, HIF2a and HIF3a in rat liver." Kietzmann T., Cornesse Y., Brechtel K., Modaressi S., Jungermann K. Biochem. J.354:531-537(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY tissue: Liver. 2. "Hypoxia rapidly activates HIF-3alpha mRNA expression." Heidbreder M., Froehlich F., Johren O., Dendorfer A., Qadri F., Dominiak P. FASEB J.17:1541-1543(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY

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SKU	Supplier No.	Size	Your price	Quantity
BHE13805366	E10271r	96T	$796		Add to Cart

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