Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
Specificity
Natural and recombinant Rat High affinity immunoglobulin epsilon receptor subunit alpha
Subcellular Location
Isoform 2 Secreted
Detection Range
78-5000pg/ml
Entryname
FCERA_RAT
Method Type
Sandwich
Protein Name
High affinity immunoglobulin epsilon receptor subunit alpha
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