ELISA Kit for Rat Heterogeneous nuclear ribonucleoprotein K

Mfr.No.	E0351r
Alternative Names	dC stretch-binding protein ; CSBP ; Hnrpk
Categories	Elisa
Function	One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA.
Specificity	Natural and recombinant Rat Heterogeneous nuclear ribonucleoprotein K
Subcellular Location	Cytoplasm Nucleus nucleoplasm
Detection Range	78-5000pg/mL
Entryname	HNRPK_RAT
Method Type	Sandwich
Platform	PF00013
Protein Name	Heterogeneous nuclear ribonucleoprotein K
Sensitivity	26pg/mL
Sequence	50: METEQPEETF ; PNTETNGEFG ; KRPAEDMEEE ; QAFKRSRNTD ; EMVELRILLQ ; 100: SKNAGAVIGK ; GGKNIKALRT ; DYNASVSVPD ; SSGPERILSI ; SADIETIGEI ; 150: LKKIIPTLEE ; GLQLPSPTAT ; SQLPLESDAV ; ECLNYQHYKG ; SDFDCELRLL ; 200: IHQSLAGGII ; GVKGAKIKEL ; RENTQTTIKL ; FQECCPHSTD ; RVVLIGGKPD ; 250: RVVECIKIIL ; DLISESPIKG ; RAQPYDPNFY ; DETYDYGGFT ; MMFDDRRGRP ; 300: VGFPMRGRGG ; FDRMPPGRGG ; RPMPPSRRDY ; DDMSPRRGPP ; PPPPGRGGRG ; 350: GSRARNLPLP ; PPPPPRGGDL ; MAYDRRGRPG ; DRYDGMVGFS ; ADETWDSAID ; 400: TWSPSEWQMA ; YEPQGGSGYD ; YSYAGGRGSY ; GDLGGPIITT ; QVTIPKDLAG ; 450: SIIGKGGQRI ; KQIRHESGAS ; IKIDEPLEGS ; EDRIITITGT ; QDQIQNAQYL ; 463: LQNSVKQYSG ; KFF
Sequence Length	463
String	P61980
Sub Unit	Identified in the spliceosome C complex. Interacts with ANKRD28 and ZIK1. Interacts with DDX1 (By similarity). Interacts with RBM42.

Reference	1. "Cloning and characterization of a single-stranded DNA binding protein that specifically recognizes deoxycytidine stretch." Ito K., Sato K., Endo H. Nucleic Acids Res.22:53-58(1994) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Donryu. tissue: Liver. 2. Lubec G., Chen W.-Q. Submitted (2007-04) to the UniProtKB [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 149-163;IDENTIFICATION BY MASS SPECTROMETRY strain: Sprague-Dawley. tissue: Hippocampus. 3. "hnRNP K interacts with RNA binding motif protein 42 and functions in the maintenance of cellular ATP level during stress conditions." Fukuda T., Naiki T., Saito M., Irie K. Genes Cells14:113-128(2009) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RBM42

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