Blocks Notch protein ; Botch ; Cation transport regulator-like protein 1 ; Neuroprotective protein 7 ; Botch ; Npg7
Categories
Elisa
Function
Negative regulator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos. May also act as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade.
Specificity
Natural and recombinant Rat Glutathione-specific gamma-glutamylcyclotransferase 1