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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Glutamate receptor 1

SKU : BHE13804923

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E11293r
Alternative Names	AMPA-selective glutamate receptor 1 ; GluR-A ; GluR-K1 ; Glutamate receptor ionotropic ; AMPA 1 ; GluA1 ; Glur1
Categories	Elisa
Function	Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Specificity	Natural and recombinant Rat Glutamate receptor 1
Subcellular Location	Cell membrane Multi-pass membrane protein Endoplasmic reticulum membrane Multi-pass membrane protein Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell junction synapse postsynaptic cell membrane postsynaptic density Cell projection dendrite Cell projection dendritic spine Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression.
Entryname	GRIA1_RAT
Method Type	Sandwich
Platform	PF01094
Protein Name	Glutamate receptor 1
Sequence	50: MPYIFAFFCT ; GFLGAVVGAN ; FPNNIQIGGL ; FPNQQSQEHA ; AFRFALSQLT ; 100: EPPKLLPQID ; IVNISDSFEM ; TYRFCSQFSK ; GVYAIFGFYE ; RRTVNMLTSF ; 150: CGALHVCFIT ; PSFPVDTSNQ ; FVLQLRPELQ ; EALISIIDHY ; KWQTFVYIYD ; 200: ADRGLSVLQR ; VLDTAAEKNW ; QVTAVNILTT ; TEEGYRMLFQ ; DLEKKKERLV ; 250: VVDCESERLN ; AILGQIVKLE ; KNGIGYHYIL ; ANLGFMDIDL ; NKFKESGANV ; 300: TGFQLVNYTD ; TIPARIMQQW ; RTSDSRDHTR ; VDWKRPKYTS ; ALTYDGVKVM ; 350: AEAFQSLRRQ ; RIDISRRGNA ; GDCLANPAVP ; WGQGIDIQRA ; LQQVRFEGLT ; 400: GNVQFNEKGR ; RTNYTLHVIE ; MKHDGIRKIG ; YWNEDDKFVP ; AATDAQAGGD ; 450: NSSVQNRTYI ; VTTILEDPYV ; MLKKNANQFE ; GNDRYEGYCV ; ELAAEIAKHV ; 500: GYSYRLEIVS ; DGKYGARDPD ; TKAWNGMVGE ; LVYGRADVAV ; APLTITLVRE ; 550: EVIDFSKPFM ; SLGISIMIKK ; PQKSKPGVFS ; FLDPLAYEIW ; MCIVFAYIGV ; 600: SVVLFLVSRF ; SPYEWHSEEF ; EEGRDQTTSD ; QSNEFGIFNS ; LWFSLGAFMQ ; 650: QGCDISPRSL ; SGRIVGGVWW ; FFTLIIISSY ; TANLAAFLTV ; ERMVSPIESA ; 700: EDLAKQTEIA ; YGTLEAGSTK ; EFFRRSKIAV ; FEKMWTYMKS ; AEPSVFVRTT ; 750: EEGMIRVRKS ; KGKYAYLLES ; TMNEYIEQRK ; PCDTMKVGGN ; LDSKGYGIAT ; 800: PKGSALRNPV ; NLAVLKLNEQ ; GLLDKLKNKW ; WYDKGECGSG ; GGDSKDKTSA ; 850: LSLSNVAGVF ; YILIGGLGLA ; MLVALIEFCY ; KSRSESKRMK ; GFCLIPQQSI ; 900: NEAIRTSTLP ; RNSGAGASGG ; GGSGENGRVV ; SQDFPKSMQS ; IPCMSHSSGM ; 907: PLGATGL
Sequence Length	907
Sub Unit	Interacts with SYNDIG1 and GRIA2 (By similarity). Homotetramer or heterotetramer of pore-forming glutamate receptor subunits. Tetramers may be formed by the dimerization of dimers. Interacts with DLG1 via its C-terminus. Interacts with CACNG2, HIP1 and probably RASGRF2. Interacts with LRFN1. Found in a complex with GRIA2, GRIA3, GRIA4, CNIH2, CNIH3, CACNG2, CACNG3, CACNG4, CACNG5, CACNG7 and CACNG8. Interacts with CNIH2, CACNG2 and CACNG5.

Uniprot	P19490
Gene Name	Gria1
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:50592
Unigene	Rn.29971

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804923	E11293r	96T	$796		Add to Cart

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