ELISA Kit for Rat Gamma-aminobutyric acid receptor subunit alpha-2

Mfr.No.	E0464r
Alternative Names	GABA(A) receptor subunit alpha-2 ; Gabra-2
Categories	Elisa
Function	GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
Specificity	Natural and recombinant Rat Gamma-aminobutyric acid receptor subunit alpha-2
Subcellular Location	Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein
Detection Range	31.2-2000pg/mL
Entryname	GBRA2_RAT
Method Type	Sandwich
Platform	PF02931
Protein Name	Gamma-aminobutyric acid receptor subunit alpha-2
Sensitivity	15.63pg/mL
Sequence	50: MRTKLSTCNV ; WFPLLVLLVW ; NPARLVLANI ; QEDEAKNNIT ; IFTRILDRLL ; 100: DGYDNRLRPG ; LGDSITEVFT ; NIYVTSFGPV ; SDTDMEYTID ; VFFRQKWKDE ; 150: RLKFKGPMNI ; LRLNNSMASK ; IWTPDTFFHN ; GKKSVAHNMT ; MPNKLLRIQD ; 200: DGTLLYTMRL ; TVQAECPMHL ; EDFPMDAHSC ; PLKFGSYAYT ; TSEVTYIWTY ; 250: NPSDSVQVAP ; DGSRLNQYDL ; LGQSIGKETI ; KSSTGEYTVM ; TAHFHLKRKI ; 300: GYFVIQTYLP ; CIMTVILSQV ; SFWLNRESVP ; ARTVFGVTTV ; LTMTTLSISA ; 350: RNSLPKVAYA ; TAMDWFIAVC ; YAFVFSALIE ; FATVNYFTKR ; GWAWDGKSVV ; 400: NDKKKEKGSV ; MIQNNAYAVA ; VANYAPNLSK ; DPVLSTISKS ; ATTPEPNKKP ; 450: ENKPAEAKKT ; FNSVSKIDRM ; SRIVFPVLFG ; TFNLVYWATY ; LNREPVLGVS ; 451: P
Sequence Length	451
Sub Unit	Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.

Reference	1. "Sequence and regional distribution of the mRNA encoding the alpha 2 polypeptide of rat gamma-aminobutyric acidA receptors." Khrestchatisky M., Maclennan A.J., Tillakaratne N.J.K., Chiang M.Y., Tobin A.J. J. Neurochem.56:1717-1722(1991) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] tissue: Brain.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804147	E0464r	96T	$796		Add to Cart