ELISA Kit for Rat Galectin-9

Mfr.No.	E0445r
Alternative Names	36 kDa beta-galactoside-binding lectin ; Urate transporter/channel ; UAT
Categories	Elisa
Function	Binds galactosides. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death (By similarity). May provide the molecular basis for urate flux across cell membranes, allowing urate that is formed during purine metabolism to efflux from cells and serving as an electrogenic transporter that plays an important role in renal and gastrointestinal urate excretion. Highly selective to the anion urate.
Specificity	Natural and recombinant Rat Galectin-9
Subcellular Location	Cytoplasm Secreted May also be secreted by a non-classical secretory pathway.
Detection Range	0.156-10ng/mL
Entryname	LEG9_RAT
Method Type	Sandwich
Platform	PF00337
Protein Name	Galectin-9
Sensitivity	0.082ng/mL
Sequence	50: MAFFSTQPPY ; MNPVIPFTGI ; IQGGLQNGLQ ; ITLQGTVHPF ; PNRIAVNFQT ; 100: GFSGNDIAFH ; FNPRFEEGGY ; VVCNTKQNGK ; WGPEERKMQM ; PFQKGMPFEL ; 150: CFLVQRSEFK ; VMVNKNFFVQ ; YSHRVPYHLV ; DTISVSGCLH ; LSFINFQNST ; 200: AAPVQPVFST ; MQFSQPVQFP ; RMPKGRKQRT ; QGFQPALQAP ; VAQTIIHTVH ; 250: SIPGQMLSTP ; GIPPMAYPTP ; AYTIPFFTSI ; PNGFYPSKSI ; NISGVVLPDA ; 300: KRFHINLRCG ; GDIAFHLNPR ; FNEKVVVRNT ; QINNSWGPEE ; RSLPGRMPFN ; 350: RGQSFSVWIL ; CEGHCFKVAV ; DGQHICEYYH ; RLKNLPDINT ; LEVAGDIQLT ; 354: HVQT
Sequence Length	354
String	P97840

Reference	1. "Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin." Wada J., Kanwar Y.S. J. Biol. Chem.272:6078-6086(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS LONG AND SHORT) strain: Sprague-Dawley. tissue: Kidney. tissue: Small intestine. 2. "Molecular cloning and functional reconstitution of a urate transporter/channel." Leal-Pinto E., Tao W., Rappaport J., Richardson M., Knorr B.A., Abramson R.G. J. Biol. Chem.272:617-625(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT) strain: Sprague-Dawley. tissue: Kidney.

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