Membrane-type receptor for bile acids ; M-BAR ; Tgr5
Categories
Elisa
Function
Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. Involved in bile acid promoted GLP1R secretion.
Specificity
Natural and recombinant Rat G-protein coupled bile acid receptor 1