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ELISA Kit for Rat Follistatin-related protein 3

SKU : BHE13804176

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0127r
Antigen	FSTL3
Alternative Names	Follistatin-like protein 3 ; Follistatin-related gene protein ; Flrg
Categories	Elisa
Function	The secreted form is a binding and antagonizing protein for members of the TGF-beta family, such us activin, BMP2 and MSTN. Inhibits activin A-, activin B-, BMP2- and MSDT-induced cellular signaling; more effective on activin A than on activin B. Involved in bone formation; inhibits osteoclast differentiation. Involved in hematopoiesis; involved in differentiation of hemopoietic progenitor cells, increases hematopoietic cell adhesion to fibronectin and seems to contribute to the adhesion of hematopoietic precursor cells to the bone marrow stroma. The nuclear form is probably involved in transcriptional regulation via interaction with MLLT10.
Specificity	Natural and recombinant Rat Follistatin-related protein 3
Subcellular Location	Secreted Nucleus
Detection Range	0.156-10ng/ml
Entryname	FSTL3_RAT
Method Type	Sandwich
Platform	PF09289
Protein Name	Follistatin-related protein 3
Sensitivity	0.088ng/mL
Sequence	50: MRPGALWPLL ; WGALVWAVGS ; VGAVMGSGDS ; VPGGVCWLQQ ; GKEATCSLVL ; 100: KTQVSREECC ; ASGNINTAWS ; NFTHPGNKIS ; LLGFLGLVHC ; LPCKDSCDGV ; 150: ECGPGKACRM ; LGGRPHCECV ; SNCEGVPAGF ; QVCGSDGATY ; RDECELRTAR ; 200: CRGHPDLRVM ; YRGRCQKSCA ; QVVCPRPQSC ; LVDQTGSAHC ; VVCRAAPCPV ; 250: PPNPGQELCG ; NNNVTYISSC ; HLRQATCFLG ; RSIGVRHPGI ; CTGGPKVPAE ; 256: EEENFV
Sequence Length	256
String	Q99PW7
Sub Unit	Interacts with INHBA and INHBB. Interacts with FN1. Interacts with ADAM12. Interacts with MLLT10; the interaction enhances MLLT10 in vitro transcriptional activity and self-association. Interacts with MSTN.

Uniprot	Q99PW7
Gene Name	Fstl3
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:114031
Unigene	Rn.48835

Reference	1. "Rat follistatin-related protein FLRG (rat PCTF35, PC12 cell derived trophic factor 35)." Uchiyama Y., Ohsawa Y., Kametaka S. Submitted (1998-12) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] 2. "Characterization of rat follistatin-related gene: effects of estrous cycle stage and pregnancy on its messenger RNA expression in rat reproductive tissues." Arai K.Y., Tsuchida K., Uehara K., Taya K., Sugino H. Biol. Reprod.68:199-206(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Wistar. tissue: Placenta.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13804176	E0127r	96T	$796		Add to Cart

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