ELISA Kit for Rat Eukaryotic peptide chain release factor subunit 1

Mfr.No.	E11482r
Categories	Elisa
Function	Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Specificity	Natural and recombinant Rat Eukaryotic peptide chain release factor subunit 1
Subcellular Location	Cytoplasm
Detection Range	0.312-20ng/ml
Entryname	ERF1_RAT
Method Type	Sandwich
Platform	PF03463
Protein Name	Eukaryotic peptide chain release factor subunit 1
Sensitivity	0.156ng/mL
Sequence	50: MADDPSAADR ; NVEIWKIKKL ; IKSLEAARGN ; GTSMISLIIP ; PKDQISRVAK ; 100: MLADEFGTAS ; NIKSRVNRLS ; VLGAITSVQQ ; RLKLYNKVPP ; NGLVVYCGTI ; 150: VTEEGKEKKV ; NIDFEPFKPI ; NTSLYLCDNK ; FHTEALTALL ; SDDSKFGFIV ; 200: IDGSGALFGT ; LQGNTREVLH ; KFTVDLPKKH ; GRGGQSALRF ; ARLRMEKRHN ; 250: YVRKVAETAV ; QLFISGDKVN ; VAGLVLAGSA ; DFKTELSQSD ; MFDQRLQSKV ; 300: LKLVDISYGG ; ENGFNQAIEL ; STEVLSNVKF ; IQEKKLIGRY ; FDEISQDTGK ; 350: YCFGVEDTLK ; ALEMGAVEIL ; IVYENLDIMR ; YVLHCQGTEE ; EKILYLTPEQ ; 400: EKDKSHFTDK ; ETGQEHELIE ; SMPLLEWFAN ; NYKKFGATLE ; IVTDKSQEGS ; 437: QFVKGFGGIG ; GILRYRVDFQ ; GMEYQGGDDE ; FFDLDDY
Sequence Length	437
String	Q5U2Q7
Sub Unit	Heterodimer of two subunits, one of which binds GTP. Component of the transient SURF (SMG1-UPF1-eRF1-eRF3) complex.

Reference	1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Heart.

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