ELISA Kit for Rat Dystrophin

Mfr.No.	E1503r
Categories	Elisa
Function	Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission.
Specificity	Natural and recombinant Rat Dystrophin
Subcellular Location	Cell membrane sarcolemma Peripheral membrane protein Cytoplasmic side Cytoplasm cytoskeleton
Detection Range	0.156-10ng/mL
Entryname	DMD_RAT
Method Type	Sandwich
Protein Name	Dystrophin
Sensitivity	0.078ng/mL
Sequence	29: AIAREKAEKF ; RKLQDASRSA ; QALVEQMVN
Sequence Length	29
String	P11530
Sub Unit	Interacts with SYNM. Interacts with the syntrophins SNTA1, SNTB1, SNTB2, SNTG1 and SNTG2. Interacts with KRT19. Component of the dystrophin-associated glycoprotein complex which is composed of three subcomplexes: a cytoplasmic complex comprised of DMD (or UTRN), DTNA and a number of syntrophins, such as SNTB1, SNTB2, SNTG1 and SNTG2, the transmembrane dystroglycan complex, and the sarcoglycan-sarcospan complex. Interacts with DAG1 (betaDAG1) with DMD; the interaction is inhibited by phosphorylation on the PPXY motif of DAG1.

Reference	1. "Expression of the putative Duchenne muscular dystrophy gene in differentiated myogenic cell cultures and in the brain." Nudel U., Robzyk K., Yaffe D. Nature331:635-638(1988) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];TISSUE SPECIFICITY

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803896	E1503r	96T	$796		Add to Cart