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ELISA Kit for Rat Dynamin-1

SKU : BHE13803726

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E1962r
Alternative Names	B-dynamin ; D100 ; Dynamin ; brain ; Dnm
Categories	Elisa
Function	Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis.
Specificity	Natural and recombinant Rat Dynamin-1
Subcellular Location	Isoform 6 Cytoplasm Golgi apparatus
Detection Range	15.6-1000ng/mL
Entryname	DYN1_RAT
Method Type	Sandwich
Platform	PF01031
Protein Name	Dynamin-1
Sensitivity	7.8ng/mL
Sequence	50: MGNRGMEDLI ; PLVNRLQDAF ; SAIGQNADLD ; LPQIAVVGGQ ; SAGKSSVLEN ; 100: FVGRDFLPRG ; SGIVTRRPLV ; LQLVNSTTEY ; AEFLHCKGKK ; FTDFEEVRLE ; 150: IEAETDRVTG ; TNKGISPVPI ; NLRVYSPHVL ; NLTLVDLPGM ; TKVPVGDQPP ; 200: DIEFQIRDML ; MQFVTKENCL ; ILAVSPANSD ; LANSDALKIA ; KEVDPQGQRT ; 250: IGVITKLDLM ; DEGTDARDVL ; ENKLLPLRRG ; YIGVVNRSQK ; DIDGKKDITA ; 300: ALAAERKFFL ; SHPSYRHLAD ; RMGTPYLQKV ; LNQQLTNHIR ; DTLPGLRNKL ; 350: QSQLLSIEKE ; VDEYKNFRPD ; DPARKTKALL ; QMVQQFAVDF ; EKRIEGSGDQ ; 400: IDTYELSGGA ; RINRIFHERF ; PFELVKMEFD ; EKELRREISY ; AIKNIHGIRT ; 450: GLFTPDLAFE ; ATVKKQVQKL ; KEPSIKCVDM ; VVSELTSTIR ; KCSEKLQQYP ; 500: RLREEMERIV ; TTHIREREGR ; TKEQVMLLID ; IELAYMNTNH ; EDFIGFANAQ ; 550: QRSNQMNKKK ; TSGNQDEILV ; IRKGWLTINN ; IGIMKGGSKE ; YWFVLTAENL ; 600: SWYKDDEEKE ; KKYMLSVDNL ; KLRDVEKGFM ; SSKHIFALFN ; TEQRNVYKDY ; 650: RQLELACETQ ; EEVDSWKASF ; LRAGVYPERV ; GDKEKASETE ; ENGSDSFMHS ; 700: MDPQLERQVE ; TIRNLVDSYM ; AIVNKTVRDL ; MPKTIMHLMI ; NNTKEFIFSE ; 750: LLANLYSCGD ; QNTLMEESAE ; QAQRRDEMLR ; MYHALKEALS ; IIGDINTTTV ; 800: STPMPPPVDD ; SWLQVQSVPA ; GRRSPTSSPT ; PQRRAPAVPP ; ARPGSRGPAP ; 850: GPPPAGSALG ; GAPPVPSRPG ; ASPDPFGPPP ; QVPSRPNRAP ; PGVPSRSGQA ; 864: SPSRPESPRP ; PFDL
Sequence Length	864
String	P21575
Sub Unit	Interacts with CAV1 and SH3GLB1. Interacts with SNX9 (By similarity). Interacts with PHOCN (By similarity). Binds SH3GL1, SH3GL2 and SH3GL3.

Uniprot	P21575
Gene Name	Dnm1
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:140694
Unigene	Rn.10354

Reference	1. "Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins." Obar R.A., Collins C.A., Hammarback J.A., Shpetner H.S., Vallee R.B. Nature347:256-261(1990) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2) strain: Sprague-Dawley. tissue: Brain. 2. Lubec G., Afjehi-Sadat L., Diao W. Submitted (2007-04) to the UniProtKB [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 5-15; 45-54; 67-87; 91-107; 116-157; 167-188; 257-266; 300-315; 328-342; 400-415; 511-522 AND 584-594 (ISOFORM 1/2/3/4);IDENTIFICATION BY MASS SPECTROMETRY strain: Sprague-Dawley. tissue: Hippocampus. tissue: Spinal cord. 3. "The in vivo phosphorylation sites of rat brain dynamin I." Graham M.E., Anggono V., Bache N., Larsen M.R., Craft G.E., Robinson P.J. J. Biol. Chem.282:14695-14707(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 343-364; 511-522 AND 797-838 (ISOFORM 1/2/4/5/6/8);PROTEIN SEQUENCE OF 847-864 (ISOFORM 1/5);PHOSPHORYLATION AT SER-347; SER-512; SER-774; SER-778; SER-822; SER-851 AND SER-857;IDENTIFICATION BY MASS SPECTROMETRY 4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 368-581 (ISOFORM 5/6/7/8) tissue: Brain. 5. "Amgen rat EST program." Amgen EST program Submitted (2003-04) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 668-864 (ISOFORM 1/5) tissue: Brain. tissue: Hypothalamus. 6. "Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis." Krendel M., Osterweil E.K., Mooseker M.S. FEBS Lett.581:644-650(2007) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MYO1E 7. "The SH3p4/Sh3p8/SH3p13 protein family: binding partners for synaptojanin and dynamin via a Grb2-like Src homology 3 domain." Ringstad N., Nemoto Y., De Camilli P. Proc. Natl. Acad. Sci. U.S.A.94:8569-8574(1997) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SH3GL1; SH3GL2 AND SH3GL3 tissue: Brain. 8. "Differential distribution of dynamin isoforms in mammalian cells." Cao H., Garcia F., McNiven M.A. Mol. Biol. Cell9:2595-2609(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING;SUBCELLULAR LOCATION;TISSUE SPECIFICITY 9. "The dephosphins: dephosphorylation by calcineurin triggers synaptic vesicle endocytosis." Cousin M.A., Robinson P.J. Trends Neurosci.24:659-665(2001) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ROLE OF PHOSPHORYLATION 10. "Interactions of phocein with nucleoside-diphosphate kinase, Eps15, and Dynamin I." Baillat G., Gaillard S., Castets F., Monneron A. J. Biol. Chem.277:18961-18966(2002) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PHOCN 11. "Cdk5 is essential for synaptic vesicle endocytosis." Tan T.C., Valova V.A., Malladi C.S., Graham M.E., Berven L.A., Jupp O.J., Hansra G., McClure S.J., Sarcevic B., Boadle R.A., Larsen M.R., Cousin M.A., Robinson P.J. Nat. Cell Biol.5:701-710(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION BY CDK5 12. "Dynamin I phosphorylation and the control of synaptic vesicle endocytosis." Smillie K.J., Cousin M.A. Biochem. Soc. Symp.72:87-97(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION 13. "Crystal structure of the GTPase domain of rat dynamin 1." Reubold T.F., Eschenburg S., Becker A., Leonard M., Schmid S.L., Vallee R.B., Kull F.J., Manstein D.J. Proc. Natl. Acad. Sci. U.S.A.102:13093-13098(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.9 ANGSTROMS) OF 6-304

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