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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat DNA topoisomerase 1

SKU : BHE13811244

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E9586r
Alternative Names	DNA topoisomerase I
Categories	Elisa
Function	The reaction catalyzed by topoisomerases leads to the conversion of one topological isomer of DNA to another. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
Specificity	Natural and recombinant Rat DNA topoisomerase 1
Subcellular Location	Nucleus nucleolus Nucleus nucleoplasm Diffuse nuclear localization with some enrichment in nucleoli. On CPT treatment, cleared from nucleoli into nucleoplasm. Sumolyated forms found in both nucleoplasm and nucleoli.
Detection Range	0.156-10ng/mL
Entryname	TOP1_RAT
Method Type	Sandwich
Platform	PF14370
Protein Name	DNA topoisomerase 1
Sensitivity	0.078ng/mL
Sequence	50: MSGDHLHNDS ; QIEADFRLND ; SHKHKDKHKD ; REHRHKEHKK ; DKDKDREKSK ; 100: HSNSEHKDSE ; KKHKEKEKTK ; HKDGSSDKHK ; DKHKDRDKEK ; RKEEKIRAAG ; 150: DAKIKKEKEN ; GFSSPPRIKD ; EPEDDGYFAP ; PKEDIKPLKR ; PRDEDDADYK ; 200: PKKIKTEDIK ; KEKKRKLEEE ; EDGKLKKPKN ; KDKDKKVAEP ; DNKKKKAKKE ; 250: EEQKWKWWEE ; ERYPEGIKWK ; FLEHKGPVFA ; PPYEPLPEGV ; KFYYDGKVMK ; 300: LSPKAEEVAT ; FFAKMLDHEY ; TTKEIFRKNF ; FKDWRKEMTN ; DEKNTITNLS ; 350: KCDFTQMSQY ; FKAQSEARKQ ; MSKEEKLKIK ; EENEKLLKEY ; GFCVMDNHRE ; 400: RIANFKIEPP ; GLFRGRGNHP ; KMGMLKRRIM ; PEDIIINCSK ; DAKVPSPPPG ; 450: HKWKEVRHDN ; KVTWLVSWTE ; NIQGSIKYIM ; LNPSSRIKGE ; KDWQKYETAR ; 500: RLKKCVDKIR ; NQYREDWKSK ; EMKVRQRAVA ; LYFIDKLALR ; AGNEKEEGET ; 550: ADTVGCCSLR ; VEHINLHPEL ; DGQEYVVEFD ; FPGKDSIRYY ; NKVPVEKRVF ; 600: KNLQLFMENK ; QPEDDLFDRL ; NTGILNKHLQ ; DLMEGLTAKV ; FRTYNASITL ; 650: QQQLKELTAP ; DENVPAKILS ; YNRANRAVAI ; LCNHQRAPPK ; TFEKSMMNLQ ; 700: SKIDAKKDQL ; ADARKDLKSA ; KADAKVMKDA ; KTKKVVESKK ; KAVQRLEEQL ; 750: MKLEVQATDR ; EENKQIALGT ; SKLNYLDPRI ; TVAWCKKWGV ; PIEKIYNKTQ ; 767: REKFAWAIDM ; TDEDYEF
Sequence Length	767
String	Q9WUL0
Sub Unit	Monomer.

Uniprot	Q9WUL0
Gene Name	Top1
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:64550
Unigene	Rn.91572

Reference	1. "Sequencing of rat topoisomerase I between sensitive and camptothecin-resistant C6 glioblastoma cell lines." Pourquier P., Gioffre C., Ueng L.-M., Robert J., Pommier Y. Submitted (1999-04) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Glioblastoma.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811244	E9586r	96T	$796		Add to Cart

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