Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
Specificity
Natural and recombinant Rat Dihydropyrimidinase-related protein 3
Subcellular Location
Cytoplasm Cell projection growth cone Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;SUBCELLULAR LOCATION;DEVELOPMENTAL STAGE;TISSUE SPECIFICITY;ALTERNATIVE SPLICING;INTERACTION WITH SYNAPTIC VESICLE PROTEIN 2 AND INTERSECTIN
"Adult-specific collapsin response mediator protein 4 (CRMP4) transcripts correlate with widespread CRMP4 expression in normal and epileptic adult rats." Elliott R.C., Parent J.M., Lowenstein D.H. Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-358 (ISOFORM 1)
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 532-550;IDENTIFICATION BY MASS SPECTROMETRY
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;SUBCELLULAR LOCATION
Reviews of ELISA Kit for Rat Dihydropyrimidinase-related protein 3