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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Copper-transporting ATPase 1

SKU : BHE13801559

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15035r
Alternative Names	Copper pump 1 ; Menkes disease-associated protein homolog ; Mnk
Categories	Elisa
Function	May supply copper to copper-requiring proteins within the secretory pathway, when localized in the trans-Golgi network. Under conditions of elevated extracellular copper, it relocalized to the plasma membrane where it functions in the efflux of copper from cells.
Specificity	Natural and recombinant Rat Copper-transporting ATPase 1
Subcellular Location	Golgi apparatus trans-Golgi network membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein Constitutively cycles between the trans-Golgi network (TGN) and the plasma membrane. Predominantly found in the TGN and relocalized to the plasma membrane in response to elevated copper levels.
Detection Range	0.156-10ng/mL
Entryname	ATP7A_RAT
Method Type	Sandwich
Platform	PF00122
Protein Name	Copper-transporting ATPase 1
Sensitivity	0.051ng/mL
Sequence	50: MEPNMDANSI ; TITVEGMTCI ; SCVRTIEQQI ; GKVNGVHHIK ; VSLEEKSATV ; 100: IYNPKLQTPK ; TLQEAIDDMG ; FDALLHNANP ; LPVLTNTVFL ; TVTAPLALPW ; 150: DHIQSTLLKT ; KGVTGVKISP ; QQRSAVVTII ; PSVVSANQIV ; ELVPDLSLDM ; 200: GTQEKKSGTS ; EEHSTPQAGE ; VLLKMRVEGM ; TCHSCTSTIE ; GKVGKLQGVQ ; 250: RIKVSLDNQE ; ATIVYQPHLI ; TAEEIKKQIE ; AVGFPAFIKK ; QPKYLKLGAI ; 300: DVERLKSTPV ; KSSEGSQQKS ; PAYPSDSAIT ; FTIDGMHCKS ; CVSNIESALS ; 350: TLQYVSSIVV ; SLENRSAIVK ; YNASLVTPEI ; LRKAIEAVSP ; GQYRVSISSE ; 400: VESPTSSPSS ; SSLQKMPLNL ; VSQPLTQEVV ; ININGMTCNS ; CVQSIEGVIS ; 450: KKPGVKSIHV ; SLTNSTGTIE ; YDPLLTSPEP ; LREAIEDMGF ; DAVLPADMKE ; 500: PLVVIAQPSL ; ETPLLPSTTE ; PENVMTPVQN ; KCYIQVSGMT ; CASCVANIER ; 550: NLRREEGIYS ; VLVALMAGKA ; EVRYNPAVIQ ; PRVIAELIRE ; LGFGAVVMEN ; 600: AGEGNGILEL ; VVRGMTCASC ; VHKIESTLTK ; HKGIFYCSVA ; LATNKAHIKY ; 650: DPEIIGPRDI ; IHTIGNLGFE ; ASLVKKDRSA ; NHLDHKREIK ; QWRGSFLVSL ; 700: FFCIPVMGLM ; IYMMVMDHHL ; ATLNHNQNMS ; NEEMINMHSS ; MFLERQILPG ; 750: LSIMNLLSLL ; LCLPVQFCGG ; WYFYIQAYKA ; LRHKTANMDV ; LIVLATTIAF ; 800: AYSLVILLVA ; MYERAKVNPI ; TFFDTPPMLF ; VFIALGRWLE ; HIAKGKTSEA ; 850: LAKLISLQAT ; EATIVTLNSE ; NLLLSEEQVD ; VELVQRGDII ; KVVPGGKFPV ; 900: DGRVIEGHSM ; VDESLITGEA ; MPVAKKPGST ; VIAGSINQNG ; SLLIRATHVG ; 950: ADTTLSQIVK ; LVEEAQTSKA ; PIQQFADKLS ; GYFVPFIVLV ; SIVTLLVWII ; 1000: IGFQNFEIVE ; AYFPGYNRSI ; SRTETIIRFA ; FQASITVLCI ; ACPCSLGLAT ; 1050: PTAVMVGTGV ; GAQNGILIKG ; GEPLEMAHKV ; KVVVFDKTGT ; ITHGTPVVNQ ; 1100: VKVLVESNKI ; SRNKILAIVG ; TAESNSEHPL ; GAAVTKYCKQ ; ELDTETLGTC ; 1150: TDFQVVPGCG ; ISCKVTNIEG ; LLHKSNLKIE ; ENNIKNASLV ; QIDAINEQSS ; 1200: PSSSMIIDAH ; LSNAVNTQQY ; KVLIGNREWM ; IRNGLVISND ; VDESMIEHER ; 1250: RGRTAVLVTI ; DDELCGLIAI ; ADTVKPEAEL ; AVHILKSMGL ; EVVLMTGDNS ; 1300: KTARSIASQV ; GITKVFAEVL ; PSHKVAKVKQ ; LQEEGKRVAM ; VGDGINDSPA ; 1350: LAMASVGIAI ; GTGTDVAIEA ; ADVVLIRNDL ; LDVVASIDLS ; RKTVKRIRIN ; 1400: FVFALIYNLI ; GIPIAAGVFL ; PIGLVLQPWM ; GSAAMAASSV ; SVVLSSLFLK ; 1450: LYRKPTYDNY ; ELRPRSHTGQ ; RSPSEISVHV ; GIDDTSRNSP ; RLGLLDRIVN ; 1492: YSRASINSLL ; SDKRSLNSVV ; TSEPDKHSLL ; VGDFREDDDT ; TL
Sequence Length	1492
String	P70705
Sub Unit	Monomer.

Uniprot	P70705
Gene Name	Atp7a
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:24941
Unigene	Rn.10554

Reference	1. "Sequence of a Menkes-type Cu-transporting ATPase from rat C6 glioma cells: comparison of the rat protein with other mammalian Cu-transporting ATPases." Qian Y., Tiffany-Castiglioni E., Harris E.D. Mol. Cell. Biochem.181:49-61(1998) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Astrocyte. 2. "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites." Hoffert J.D., Pisitkun T., Wang G., Shen R.-F., Knepper M.A. Proc. Natl. Acad. Sci. U.S.A.103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-1204;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801559	E15035r	96T	$796		Add to Cart

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