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Home / Assay Kits / ELISA Kits

ELISA Kit for Rat Coagulation factor XII

SKU : BHE13803770

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E0694r
Alternative Names	Hageman factor ; HAF
Categories	Elisa
Function	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa.
Specificity	Natural and recombinant Rat Coagulation factor XII
Subcellular Location	Secreted
Detection Range	0.78-50ng/mL
Entryname	FA12_RAT
Method Type	Sandwich
Platform	PF00008
Protein Name	Coagulation factor XII
Sensitivity	0.45ng/mL
Sequence	50: MTALLFLGSL ; LMSLDLTLSA ; PPWKSKEFKD ; GAGDPSVVLT ; VDGKLCHFPF ; 100: QYHRRLYHKC ; IHKGQPGSRP ; WCATTPNFDE ; DQQWGYCLEP ; KKVKDHCSKH ; 150: SPCHKGGTCV ; NTPNGPHCLC ; PEHLTGKHCQ ; REKCFESQLL ; KFFHENEIWF ; 200: RTGPGGVARC ; QCKGPQAVCK ; LLTSQVCRVN ; PCLNGGTCLL ; VEDHRLCHCP ; 250: AGYAGPFCDL ; DLKATCYEDR ; GLSYRGQAKT ; TLSGAPCQRW ; ASEATYRNMT ; 300: ETQALSWGLG ; HHAFCRNPDN ; DTRPWCYVWS ; GDRLSWDYCD ; LEQCQMPTLT ; 350: SPVSPESHDM ; LKPRPPILQS ; SPRDSTRNQN ; VVSRTSTVVC ; GQRFRKRLSS ; 400: LRRVVGGLVA ; LPGSHPYIAA ; LYWGDSFCAG ; SLIDPCWVLT ; AAHCLQKRPA ; 450: PEELTVVLGQ ; DRHNQSCERC ; QTLAVHSYRL ; HEGFSSKTYQ ; HDLALLRLRG ; 500: RKNSCAILSP ; HVQPVCLPSS ; AAPPSETVLC ; EVAGWGHQFE ; GAEEYATFLQ ; 550: EAQVPFISLD ; RCSSSNVHGD ; AILPGMLCAG ; FLEGGADACQ ; GDSGGPLVCD ; 595: EGVTERQLTL ; RGVISWGSGC ; GDRNKPGVYT ; DVANYLDWIQ ; EHTAF
Sequence Length	595
Sub Unit	Interacts with HRG; the interaction, which is enhanced in the presence of zinc ions and inhibited by heparin-binding, inhibits factor XII autoactivation and contact-initiated coagulation.

Uniprot	D3ZTE0
Gene Name	F12
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:306761
Unigene	Rn.53943

Reference	1. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (2005-07) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] tissue: Liver.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13803770	E0694r	96T	$796		Add to Cart

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