ELISA Kit for Rat Bone morphogenetic protein 10

Mfr.No.	E1115r
Categories	Elisa
Function	Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth.
Specificity	Natural and recombinant Rat Bone morphogenetic protein 10
Subcellular Location	Secreted
Detection Range	0.156-10ng/mL
Entryname	BMP10_RAT
Method Type	Sandwich
Platform	PF00019
Protein Name	Bone morphogenetic protein 10
Sensitivity	0.085ng/mL
Sequence	50: MGSLVLPLSA ; VFCLVARLAS ; GSPIMGLEQS ; PLEEDMPFFD ; DIFTEQDGID ; 100: FNTLLQSMKD ; EFLKTLNLSD ; IPPQDTGRVD ; PPEYMLELYN ; KFATDRTSMP ; 150: SANIIRSFKN ; EDLFSQPVSF ; NGIRKYPLLF ; NVSIPHHEEV ; VMAELRLYTL ; 200: VQRDRLMYDG ; VDRKIIIFEV ; LESADGSEDE ; RSMLVLVSTE ; IYGTNSEWET ; 250: FDITDATRRW ; QKSGPSTHQL ; EIHIESRQNQ ; AEDTGRGQLE ; IDMSAQNKHD ; 300: PLLVVFSDDQ ; SGDKEQKEEL ; NELISHEQDL ; DLGTDGFFGG ; PDEEALLQMR ; 350: SNMIDDSTAR ; IRRNAKGNYC ; KKTPLYIDFK ; EIGWDSWIIA ; PPGYEAYECR ; 400: GVCNYPLAEH ; LTPTKHAIIQ ; ALVHLKNSQK ; ASKACCVPTK ; LDPISILYLD ; 421: KGVVTYKFKY ; EGMAVSECGC ; R
Sequence Length	421
String	Q4AEG6
Sub Unit	Homodimer; disulfide-linked.

Reference	1. "Fine mapping of radiation susceptibility and gene expression analysis of LEC congenic rat lines." Tsuji A.B., Sugyo A., Ogiu T., Sagara M., Kimura T., Ishikawa A., Sudo H., Ohtsuki M., Aburatani H., Imai T., Harada Y.N. Genomics86:271-279(2005) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] strain: Fischer 344/DuCrj. strain: LEC/Crj.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13801778	E1115r	96T	$796		Add to Cart