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ELISA Kit for Rat ATP-binding cassette sub-family A member 7

SKU : BHE13800416

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15004r
Categories	Elisa
Function	Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation.
Specificity	Natural and recombinant Rat ATP-binding cassette sub-family A member 7
Subcellular Location	Cell membrane Multi-pass membrane protein Golgi apparatus membrane Multi-pass membrane protein Endosome membrane Multi-pass membrane protein Localizes to cell membrane ruffles and phagocytic cups of macrophages stimulated with C1q or apoptotic cells. Localizes to the cytoplasm of resting macrophages, probably in Golgi and endosomes. Localizes to the apical brush border of cells in the proximal tubules of kidney.
Detection Range	0.156-10ng/mL
Entryname	ABCA7_RAT
Method Type	Sandwich
Platform	PF00005
Protein Name	ATP-binding cassette sub-family A member 7
Sensitivity	0.061ng/mL
Sequence	50: MAFCTQLMLL ; LWKNYTYRRR ; QPIQLVVELL ; WPLFLFFILV ; AVRHSHPPLE ; 100: HHECHFPNKP ; LPSAGTVPWL ; QGLVCNVNNS ; CFQHPTPGEK ; PGVLSNFKDS ; 150: LISRLLADAH ; TVLGGHSTQD ; MLAALGKLIP ; VLRAVGSGAW ; PQESNQPAKQ ; 200: GSVTELLEKI ; LQRASLETVL ; GQAQDSMRKF ; SDATRTVAQE ; LLTLPSLVEL ; 250: RALLRRPRGS ; AGSLELISEA ; LCSTKGPSSP ; GGLSLNWYEA ; NQINEFMGPE ; 300: LAPTLPDSSL ; SPACSEFVGA ; LDDHPVSRLL ; WRRLKPLILG ; KILFAPDTNF ; 350: TRKLMAQVNQ ; TFEELALLRD ; LHELWGVLGP ; QIFNFMNDST ; NVAMLQKLLD ; 400: VEGTGWQQQT ; PKGQKQLEAI ; RDFLDPSRGR ; YNWQEAHADM ; GRLAEILGQI ; 450: LECVSLDKLE ; AVPSEEALVS ; RALELLGERR ; LWAGIVFLSP ; EHPLDSSEPP ; 500: SPTTTGPGHL ; RVKIRMDIDD ; VTRTNKIRDK ; FWDPGPSADP ; LMDLRYVWGG ; 550: FVYLQDLLEQ ; AAVRVLSGRD ; SRAGLYLQQM ; PHPCYVDDVF ; LRVLSRSLPL ; 600: FLTLAWIYSV ; ALTVKAVVRE ; KETRLRETMR ; AMGLSRAVLW ; LGWFLSCLGP ; 650: FLVSAALLVL ; VLKLGNILPY ; SHPVVVFLFL ; AAFAVATVAQ ; SFLLSAFFSR ; 700: ANLAAACGGL ; AYFALYLPYV ; LCVAWRERLP ; LGGLLAVSLL ; SPVAFGFGCE ; 750: SLALLEEQGD ; GAQWHNLGTG ; PAEDVFSLAQ ; VSAFLLLDAV ; IYGLALWYLE ; 800: AVCPGQYGIP ; EPWNFPFRRS ; YWCGPGPPKS ; SVLAPAPQDP ; KVLVEEPPPG ; 850: LVPGVSIRGL ; KKHFRGSPQP ; ALRGLNLDFY ; EGHITAFLGH ; NGAGKTTTLS ; 900: ILSGLFPPSS ; GSASILGHDV ; QTNMAAIRPH ; LGICPQYNVL ; FDMLTVEEHV ; 950: WFYGRLKGVS ; AAAIDSEQEH ; LIRDVGLIPK ; RDTQTRHLSG ; GMQRKLSVAI ; 1000: AFVGGSRVVI ; MDEPTAGVDP ; ASRRGIWELL ; LKYREGRTLI ; LSTHHLDEAE ; 1050: LLGDRVAMVA ; SGSLCCCGSP ; LFLRRHLGCG ; YYLTLVKSSQ ; SLVTHDLKGD ; 1100: TEDPRREKKS ; GSEGKTADTV ; LTRDGPHRSS ; QVPAPDAVPV ; TPSAALILEL ; 1150: VQRHVPGAQL ; VEELPHELVL ; ALPYAGALDG ; SFATVFQELD ; QQLERLGLTG ; 1200: YGISDTNLEE ; IFLKVVEEAH ; AHGEGGDPRQ ; QQHLLTATPQ ; PHTGPEASVL ; 1250: ENGELAKLVL ; DPQAPKGSAP ; TTAQVQGWTL ; TCQQLRALLH ; KRFLLARRSR ; 1300: RGLFAQIVLP ; ALFVGLALFF ; TLIVPPFGQY ; PPLQLSPAMY ; GPQVSFFSED ; 1350: APADPNRMKL ; LEALLGEAGL ; QDPSVQGKGS ; RGSECTHSLA ; CYFTVPEVPP ; 1400: DVASILASGN ; WTPDSPSPAC ; QCSQPGARRL ; LPDCPAGAGG ; PPPPQAMAGF ; 1450: GEVVQNLTGR ; NVSDFLVKTY ; PSLVRRGLKT ; KKWVDEVRYG ; GFSLGGRDPD ; 1500: LPSGREVVRT ; VAEMRALLSP ; QPGNTLDRIL ; NNLTQWALGL ; DARNSLKIWF ; 1550: NNKGWHAMVA ; FVNRANNGLL ; RAFLPSGSVR ; HAHSITTLNH ; PLNLTKEQLS ; 1600: EATLIASSVD ; VLVSICVVFA ; MSFVPASFTL ; VLIEERITRA ; KHLQLVSGLP ; 1650: QTLYWLGNFL ; WDMCNYLVAV ; CIVVLIFLAF ; QQKAYVAPEN ; LPALLLLLLL ; 1700: YGWSITPLMY ; PASFFFSVPS ; TAYVVLTCIN ; LFIGINSSMA ; TFVLELLSDQ ; 1750: NLQEVSRILK ; QVFLIFPHFC ; LGRGLIDMVR ; NQAMADAFER ; LGDKQFQSPL ; 1800: RWDIIGKNLL ; AMVAQGPLFL ; LITLLLQHRN ; RLLPQPKSRL ; PPPLGEEDED ; 1850: VVRERERVTK ; GATQGDVLVL ; RDLTKVYRGQ ; RSPAVDHLCL ; GIPPGECFGL ; 1900: LGVNGAGKTS ; TFRMVTGDTL ; PSSGEAVLAG ; HNVAQEPSAA ; HRSMGYCPQS ; 1950: DAIFDLLTGR ; EHLELFARLR ; GVPEAQVAQT ; ALSGLVRLGL ; PSYADRPAGT ; 2000: YSGGNKRKLA ; TALALVGDPA ; VVFLDEPTTG ; MDPSARRFLW ; NNLLSVVREG ; 2050: RSVVLTSHSM ; EECEALCTRL ; AIMVNGRFRC ; LGSAQHLKSR ; FGAGHTLTLR ; 2100: VPPDQPEPAI ; AFIVTTFPDA ; ELREVHGSRL ; RFQLPPGGGC ; TLARVFRELA ; 2150: AQGKAHGVED ; FSVSQTTLEE ; VFLYFSKDQG ; EEEEGSGQET ; ETREVSTPGL ; 2170: QHPKRVSRFL ; EDPSSVETVI ;
Sequence Length	2170
String	Q7TNJ2

Uniprot	Q7TNJ2
Gene Name	Abca7
Immunogen Species	Rattus norvegicus (Rat)
Kegg	rno:299609
Unigene	Rn.25281

Reference	1. "Cloning of rat ABCA7 and its preferential expression in platelets." Sasaki M., Shoji A., Kubo Y., Nada S., Yamaguchi A. Biochem. Biophys. Res. Commun.304:777-782(2003) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY strain: Wistar. tissue: Platelet.

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