Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is intealized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then retus to the cell membrane surface.
Specificity
Natural and recombinant Rat Asialoglycoprotein receptor 1