Activin receptor type IIA ; ACTR-IIA ; Actrii ; Acvr2
Categories
Elisa
Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
Specificity
Natural and recombinant Rat Activin receptor type-2A