ELISA Kit for Pig Voltage-dependent anion-selective channel protein 1

Mfr.No.	E12942p
Categories	Elisa
Function	Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Specificity	Natural and recombinant Pig Voltage-dependent anion-selective channel protein 1
Subcellular Location	Mitochondrion outer membrane Cell membrane
Entryname	VDAC1_PIG
Platform	PF01459
Protein Name	Voltage-dependent anion-selective channel protein 1
Sequence	50: MAVPPTYADL ; GKSARDVFTK ; GYGFGLIKLD ; LKTKSENGLE ; FTSSGSANTE ; 100: TTKVTGSLET ; KYRWTEYGLT ; FTEKWNTDNT ; LGTEITVEDQ ; LARGLKLTFD ; 150: SSFSPNTGKK ; NAKIKTGYKR ; EHVNLGCDVD ; FDIAGPSIRG ; ALVLGYEGWL ; 200: AGYQMNFETA ; KSRVTQSNFA ; VGYKTDEFQL ; HTNVNDGTEF ; GGSIYQKVNK ; 250: KLETAVNLAW ; TAGNSNTRFG ; IAAKYQIDPD ; ACFSAKVNNS ; SLIGLGYTQT ; 283: LKPGIKLTLS ; ALLDGKNVNA ; GGHKLGLGLE ; FQA
Sequence Length	283
String	Q9MZ16
Sub Unit	Interacts with hexokinases (By similarity). Interacts with BCL2L1.

Reference	1. "Ion channels in the lens." Rae J.L. Submitted (2000-05) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Lens.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13811941	E12942p	96T	$900		Add to Cart