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Home / Assay Kits / ELISA Kits

ELISA Kit for Pig Solute carrier family 22 member 1

SKU : BHE13810004

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EIAAB SCIENCE INC, WUHAN

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Mfr.No.	E15326p
Alternative Names	Organic cation transporter 1 ; pOCT1 ; OCT1
Categories	Elisa
Function	Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)-N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH-independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase.
Specificity	Natural and recombinant Pig Solute carrier family 22 member 1
Subcellular Location	Basolateral cell membrane Multi-pass membrane protein
Entryname	S22A1_PIG
Platform	PF00083
Protein Name	Solute carrier family 22 member 1
Sequence	50: MPSVDDVLEQ ; VGEFGWFQKQ ; AFLNLCLTSV ; AFAPIYVGIV ; FLGFTPDHRC ; 100: RSPGVAELSQ ; RCGWSLAEEL ; NYTVPGLGPA ; GQAFPRQCRR ; YEVDWNQSTL ; 150: GCEDPLAGLA ; ANSSHLPLGP ; CQYGWVYDTP ; GSSIVTEFNL ; VCEAAWKVDL ; 200: FQSCVNVGFF ; VGSMGIGYIA ; DRLVGSSASW ; PPPHQCRLGR ; PDAVAPDYVS ; 250: LLVFRLLQGL ; VSKGSWMAGY ; TLITEFVGLG ; YRKTVAILYQ ; TAFSVGLVLL ; 300: SGLAYAVPHW ; RSLQLAVSLP ; IFLLLLCYWF ; VPESPRWLLS ; QKRNTQAIKI ; 350: MDRIAQKNGK ; LPPADLKMLS ; LEEEVVTERL ; SPSFLDLFRT ; QNLRKYTFIL ; 400: MYLWFTSSVL ; YQGLIMHVGA ; TGGSLYLDFL ; YSALVEFPAA ; FVILLIIDRF ; 450: GRLYLLAGSN ; LLAGAACFFM ; IFISHDLHWL ; SIVAACIGRM ; GITIVFQMVC ; 500: LVSAELYPTF ; IRNLGVMVCS ; SLCDLGGVVA ; PFLVFRLTEV ; WRGLPLVLFA ; 550: ALGLVAGGMS ; LLLPETKGVA ; LPETIEEVER ; LGRKAKPRDN ; MIYLQVKMPE ; 554: PAGL
Sequence Length	554

Uniprot	Q863T6
Gene Name	SLC22A1
Immunogen Species	Sus Scrofa (Pig)
Kegg	ssc:397049
Unigene	Ssc.23507

Reference	1. "Molecular and functional characterization of pig kidney OCT1." Honscha K.U., Aschenbach J.R., Gabel G. Submitted (2003-02) to the EMBL/GenBank/DDBJ databases [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] tissue: Kidney.

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SKU	Supplier No.	Size	Your price	Quantity
BHE13810004	E15326p	96T	$900		Add to Cart

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