ELISA Kit for Pig Disintegrin and metalloproteinase domain-containing protein 17

Mfr.No.	E1319p
Alternative Names	TNF-alpha convertase ; TNF-alpha-converting enzyme ; CD156b ; TACE
Categories	Elisa
Function	Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface (By similarity). Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Also involved in the activation of Notch pathway.
Specificity	Natural and recombinant Pig Disintegrin and metalloproteinase domain-containing protein 17
Subcellular Location	Membrane Single-pass type I membrane protein
Detection Range	78-5000pg/mL
Entryname	ADA17_PIG
Method Type	Sandwich
Protein Name	Disintegrin and metalloproteinase domain-containing protein 17
Sensitivity	23pg/mL
Sequence	50: MLREQFSFDI ; AEEASKVCLA ; HLFTYQDFDM ; GTLGLAYVGS ; PRANSHGGVC ; 100: PKAYYSPIGK ; KNIYLNSGLT ; STKNYGKTIL ; TKEADLVTTH ; ELGHNFGAEH ; 112: DPDGLAECAP ; NE
Sequence Length	112
String	O77636
Sub Unit	Interacts with MAD2L1 and MUC1.

Reference	1. "Effects of culture conditions and exposure to catabolic stimulators (IL-1 and retinoic acid) on the expression of matrix metalloproteinases (MMPs) and disintegrin metalloproteinases (ADAMs) by articular cartilage chondrocytes." Flannery C.R., Little C.B., Caterson B., Hughes C.E. Matrix Biol.18:225-237(1999) [PubMed] [Europe PMC] [Abstract] [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]

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SKU	Supplier No.	Size	Your price	Quantity
BHE13800528	E1319p	96T	$900		Add to Cart