Adhesion plaque protein. Binds alpha-actinin and the CRP protein. Important for targeting TES and ENA/VASP family members to focal adhesions and for the formation of actin-rich structures. May be a component of a signal transduction pathway that mediates adhesion-stimulated changes in gene expression.
Specificity
Natural and recombinant Mouse Zyxin
Subcellular Location
Cytoplasm Cytoplasm cytoskeleton Cell junction focal adhesion Nucleus Associates with the actin cytoskeleton near the adhesion plaques. Enters the nucleus in the presence of HESX1.